HitPredict

Interactor 1: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0061630 - ubiquitin protein ligase activity GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 311 Hs			1 522
+	Hs
		865099 TTC3_HUMAN (22-300): 1.94e-27: 114: 15.16		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		1024750 RN126_HUMAN (1-311): 3.19e-81: 250: 100.00		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		1290878 RN126_HUMAN (1-311): 3.19e-81: 250: 100.00		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Hs
		1019364 RN126_HUMAN (1-311): 3.19e-81: 250: 100.00		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		585062 RNF38_HUMAN (55-272): 8.94e-35: 133: 25.11		RO52_HUMAN (64-403): 5.77e-45: 166: 14.97
+	Hs
		302053 RNF6_HUMAN (33-281): 5.22e-34: 133: 21.43		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		537137 RNF6_HUMAN (33-281): 5.22e-34: 133: 21.43		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		1327692 RNF38_HUMAN (55-272): 8.94e-35: 133: 25.11		RN114_HUMAN (63-232): 4.73e-33: 127: 19.13