HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	37071664
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1834 Hs			1 2442
+	Hs
		1314485 SLX4_HUMAN (1-1834): 0: 1473: 100.00		TRI33_HUMAN (614-1207): 1.09e-36: 154: 13.64
+	Hs
		180868 SLX4_HUMAN (1-1834): 0: 1473: 100.00		TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97
+	Hs
		674239 SLX4_HUMAN (1-1834): 0: 1473: 100.00		BRD2_HUMAN (1065-1195): 9.69e-34: 143: 30.53
+	Hs
		1253860 SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50		CBP_HUMAN (1-2442): 0: 1096: 100.00
+	Hs
		1129671 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		CBP_HUMAN (1-2442): 0: 1096: 100.00
+	Hs
		861238 MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90		CBP_HUMAN (1-2442): 0: 1096: 100.00
+	Hs
		854068 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89
+	Hs
		180852 SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50		TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97
+	Hs
		1129788 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		TRI33_HUMAN (614-1207): 1.09e-36: 154: 13.64
+	Hs
		1129599 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89
+	Hs
		674162 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		BRD2_HUMAN (1065-1195): 9.69e-34: 143: 30.53
+	Hs
		590235 MUC1_HUMAN (870-1755): 3.14e-23: 110: 10.32		MUC1_HUMAN (1841-2425): 1.24e-24: 115: 13.64
+	Dm
		119660 M9PB30_DROME (814-1463): 1.62e-28: 128: 10.28		M9PB30_DROME (1836-2241): 2.87e-17: 91.8: 13.38
+	Hs
		854358 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19
+	Hs
		590279 MUC1_HUMAN (870-1755): 3.14e-23: 110: 10.32		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Hs
		1067448 SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Mm
		1455913 PCLO_MOUSE (836-1825): 7.2e-16: 86.7: 10.09		PCLO_MOUSE (9-1091): 4.6e-11: 71: 8.82
+	Hs
		1067330 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Hs
		161491 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		KMT2C_HUMAN (1839-2361): 2.29e-10: 68.7: 10.22
+	Hs
		161457 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61