HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19596235
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1834 Hs			1 1507
+	Hs
		965081 SLX4_HUMAN (1-1834): 0: 1473: 100.00		WDR5_HUMAN (923-1244): 9.83e-46: 170: 13.02
+	Hs
		209299 SLX4_HUMAN (1-1834): 0: 1473: 100.00		PRP4_HUMAN (1178-1389): 6.85e-30: 128: 11.74
+	Hs
		992849 SLX4_HUMAN (1-1834): 0: 1473: 100.00		RACK1_HUMAN (1049-1209): 4.43e-28: 118: 10.86
+	Hs
		161490 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		POC1A_HUMAN (1010-1244): 1.16e-49: 184: 12.75
+	Hs
		161443 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		WDR5_HUMAN (923-1244): 9.83e-46: 170: 13.02
+	Hs
		854343 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		NLE1_HUMAN (972-1164): 4.77e-28: 122: 14.43
+	Hs
		1273854 MICA3_HUMAN (1139-1747): 8.47e-13: 76.3: 10.24		FBXW7_HUMAN (1039-1242): 7.71e-37: 151: 9.64
+	Hs
		853980 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		RACK1_HUMAN (1049-1209): 4.43e-28: 118: 10.86
+	Hs
		161502 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		FBXW7_HUMAN (1039-1242): 7.71e-37: 151: 9.64
+	Hs
		1380165 PRR36_HUMAN (829-1588): 8.6e-09: 62.8: 9.86		FBXW7_HUMAN (1039-1242): 7.71e-37: 151: 9.64
+	Hs
		992751 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		RACK1_HUMAN (1049-1209): 4.43e-28: 118: 10.86
+	Hs
		161486 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		WDR5B_HUMAN (1207-1379): 4.28e-28: 118: 10.33