HitPredict

Interactor 1: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Interactor 2: MED20 (Q9H944)
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)
Gene: MED20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	24981860, 33961781, 26186194, 28514442, 32707033, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 502 Hs			1 212
+	Hs
		826358 CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69		MED20_HUMAN (1-212): 9.56e-115: 327: 100.00
+	Hs
		73042 B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00		MED20_HUMAN (1-212): 9.56e-115: 327: 100.00
+	Dm
		954647 CDK8_DROME (1-413): 7.19e-138: 407: 77.24		MED20_DROME (1-203): 1.86e-87: 260: 38.29