HitPredict

Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1426 Hs			1 165
+	Hs
		131726 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71
+	Hs
		131710 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55
+	Hs
		131736 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX4_HUMAN (82-165): 1.58e-12: 65.8: 18.75
+	Hs
		131749 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX3_HUMAN (15-78): 1.96e-10: 60.1: 23.08
+	Hs
		131702 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX1_HUMAN (12-77): 4.61e-10: 58.9: 23.88
+	Hs
		131751 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX6_HUMAN (82-165): 9.62e-10: 57.7: 18.75
+	Hs
		131704 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX2_HUMAN (15-85): 1.62e-09: 57.4: 25.00
+	Hs
		131737 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		ISL2_HUMAN (76-152): 4.78e-09: 55.8: 16.88
+	Hs
		903746 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00
+	Hs
		899924 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55
+	Hs
		1281194 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX4_HUMAN (82-165): 1.58e-12: 65.8: 18.75
+	Hs
		1350240 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX3_HUMAN (15-78): 1.96e-10: 60.1: 23.08
+	Hs
		822688 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX1_HUMAN (12-77): 4.61e-10: 58.9: 23.88
+	Hs
		839836 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX2_HUMAN (15-85): 1.62e-09: 57.4: 25.00
+	Hs
		1200125 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX4_HUMAN (82-165): 1.58e-12: 65.8: 18.75
+	Hs
		1200133 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX6_HUMAN (82-165): 9.62e-10: 57.7: 18.75
+	Hs
		839774 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX2_HUMAN (15-85): 1.62e-09: 57.4: 25.00
+	Hs
		1200126 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		ISL2_HUMAN (76-152): 4.78e-09: 55.8: 16.88
+	Hs
		822650 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX1_HUMAN (12-77): 4.61e-10: 58.9: 23.88
+	Hs
		839785 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX2_HUMAN (15-85): 1.62e-09: 57.4: 25.00