Interactor 1: SDHA (Q8K2B3)
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) (Malate dehydrogenase [quinone] flavoprotein subunit) (EC 1.1.5.-)
Gene: SDHA

Interactor 2: SDHB (Q9CQA3)
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) (Malate dehydrogenase [quinone] iron-sulfur subunit) (EC 1.1.5.-)
Gene: SDHB

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29222160, 29199018, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FAD_binding_2~Fer2_3, FAD_binding_2~Fer4_17, Fer2_3~Succ_DH_flav_C
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006099 - tricarboxylic acid cycle
GO:0006105 - succinate metabolic process
GO:0006121 - mitochondrial electron transport, succinate to ubiquinone
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 664
Mm

1 282
+ Hs
+ Sc
+ Sc
+ Ec
+ Hp
+ Ec
+ Nv

Service provided by Combinatics, Japan

Last updated: 11Aug2025