HitPredict

Interactor 1: KRA42 (Q9BYR5)
Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2)
Gene: KRTAP4-2

Interactor 2: SHFL (Q9NUL5)
Shiftless antiviral inhibitor of ribosomal frameshifting protein (SFL) (SHFL) (Interferon-regulated antiviral protein) (IRAV) (Repressor of yield of DENV protein) (RyDEN)
Gene: SHFL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 291
+	Hs
		1309024 KR412_HUMAN (2-136): 5.17e-26: 98.6: 64.38		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1216400 KRA13_HUMAN (3-135): 4.44e-22: 87.4: 34.57		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1317397 KRA15_HUMAN (3-136): 4.22e-21: 85.1: 30.06		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1317327 KRA44_HUMAN (2-126): 5.32e-21: 84.7: 50.40		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		889130 KR105_HUMAN (26-135): 1.38e-16: 75.4: 36.80		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		889012 KR103_HUMAN (35-136): 1.08e-16: 74.7: 36.36		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1317258 KRA93_HUMAN (29-134): 6.33e-17: 73.9: 42.73		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		889416 KR107_HUMAN (16-136): 3.47e-14: 69.7: 29.63		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1317316 KRA45_HUMAN (2-136): 1.64e-14: 68.1: 41.21		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		889700 KR108_HUMAN (14-136): 9.72e-14: 67.4: 27.48		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		889905 KR109_HUMAN (4-116): 3e-13: 66.6: 30.53		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1317280 KRA92_HUMAN (33-134): 1.36e-13: 65.8: 43.20		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1317298 KR411_HUMAN (52-136): 3.68e-13: 65: 47.06		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		888783 KR101_HUMAN (51-135): 9.54e-11: 59.3: 35.48		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		1317389 KRA24_HUMAN (19-135): 7.72e-11: 57.3: 31.20		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		473348 KRA23_HUMAN (19-135): 7.72e-11: 57.3: 31.20		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		888625 KR123_HUMAN (51-136): 9.22e-11: 56.6: 33.33		SHFL_HUMAN (1-291): 0: 620: 100.00
+	Hs
		991680 KRA11_HUMAN (3-124): 1.33e-09: 55: 24.81		SHFL_HUMAN (1-291): 0: 620: 100.00