HitPredict

Interactor 1: NLE1 (P25382)
Ribosome assembly protein 4 (Notchless protein homolog 1) (Ribosome biogenesis factor RSA4)
Gene: RSA4

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23874617
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 515 Sc			1 505
+	Sc
		673554 NLE1_YEAST (1-515): 7.7e-149: 437: 100.00		DRS1_YEAST (26-394): 3.81e-72: 245: 38.32
+	Hs
		1369406 NLE1_HUMAN (212-514): 7.7e-78: 253: 23.16		DDX17_HUMAN (4-421): 3.07e-132: 402: 31.75
+	Sc
		673547 NLE1_YEAST (1-515): 7.7e-149: 437: 100.00		SPB4_YEAST (56-488): 1.91e-61: 213: 33.41
+	Sc
		632627 PWP2_YEAST (4-274): 9.95e-42: 161: 12.54		DBP4_YEAST (3-501): 5.54e-165: 487: 37.70
+	Sc
		678448 PWP2_YEAST (4-274): 9.95e-42: 161: 12.54		HAS1_YEAST (1-505): 9.17e-165: 477: 100.00
+	Sc
		444437 PWP2_YEAST (4-274): 9.95e-42: 161: 12.54		DED1_YEAST (20-418): 3.6e-138: 413: 27.85
+	Hs
		1436289 NLE1_HUMAN (212-514): 7.7e-78: 253: 23.16		DDX31_HUMAN (9-505): 3.74e-82: 274: 32.37
+	Hs
		1369337 FBXW7_HUMAN (18-209): 4.4e-25: 111: 13.00		DDX17_HUMAN (4-421): 3.07e-132: 402: 31.75
+	Hs
		965274 WDR5_HUMAN (1-122): 1.77e-18: 88.6: 9.45		DDX18_HUMAN (2-492): 2.67e-138: 415: 59.76
+	Hs
		141604 FBXW7_HUMAN (18-209): 4.4e-25: 111: 13.00		DDX3X_HUMAN (4-428): 1.05e-126: 385: 27.77
+	Hs
		1392247 NLE1_HUMAN (212-514): 7.7e-78: 253: 23.16		DDX27_HUMAN (44-441): 6.78e-71: 242: 37.04
+	Hs
		965133 WDR5_HUMAN (1-122): 1.77e-18: 88.6: 9.45		DDX17_HUMAN (4-421): 3.07e-132: 402: 31.75
+	Hs
		608525 WDR5_HUMAN (1-122): 1.77e-18: 88.6: 9.45		DDX5_HUMAN (4-449): 1.91e-131: 396: 30.67
+	Hs
		193129 POC1A_HUMAN (432-513): 7.04e-20: 93.6: 35.37		DDX3Y_HUMAN (4-434): 6.6e-126: 383: 26.95
+	Hs
		141400 WDR5_HUMAN (1-122): 1.77e-18: 88.6: 9.45		DDX3X_HUMAN (4-428): 1.05e-126: 385: 27.77
+	Hs
		141711 FBW1A_HUMAN (154-389): 7.92e-18: 88.6: 27.66		DDX3X_HUMAN (4-428): 1.05e-126: 385: 27.77
+	Hs
		984272 GBB2_HUMAN (293-514): 1.04e-34: 135: 20.61		DDX47_HUMAN (1-411): 5.6e-74: 242: 36.96
+	Sc
		678362 PWP2_YEAST (4-274): 9.95e-42: 161: 12.54		SPB4_YEAST (56-488): 1.91e-61: 213: 33.41
+	Hs
		965160 WDR5_HUMAN (1-122): 1.77e-18: 88.6: 9.45		DDX27_HUMAN (44-441): 6.78e-71: 242: 37.04
+	Hs
		965230 WDR5_HUMAN (1-122): 1.77e-18: 88.6: 9.45		DDX47_HUMAN (1-411): 5.6e-74: 242: 36.96