HitPredict

Interactor 1: IRAK3 (Q8K4B2)
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)
Gene: IRAK3

Interactor 2: IRAK3 (Q8K4B2)
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)
Gene: IRAK3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 12054681
Identification Methods in-gel kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, Pkinase~Pkinase
Common GO terms GO:0000287 - magnesium ion binding
GO:0001819 - positive regulation of cytokine production
GO:0001960 - negative regulation of cytokine-mediated signaling pathway
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
and 25 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 609
Mm

1 609
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ At
+ At
+ Mm
+ Hs
+ Hs
+ Mm

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Last updated: 11Aug2025