Protein: IRAK4
Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1)

Gene: IRAK4
Organism: Mus musculus
Interactions: 11
UniProt ID: Q8R4K2

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002446 - neutrophil mediated immunity
GO:0004674 - protein serine/threonine kinase activity
GO:0005149 - interleukin-1 receptor binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1224128

IRAK1
Interleukin-1 receptor-associated kinase 1

3

20

Small-scale

0.829

High

562918

IL1R1
Interleukin-1 receptor type 1

2

6

Small-scale

0.754

High

648071

MYD88
Myeloid differentiation primary response protein MyD88

6

20

Small-scale

0.728

High

1341614

TLR4
Toll-like receptor 4

1

20

Small-scale

0.665

High

849111

ZAP70
Tyrosine-protein kinase ZAP-70

1

1

Small-scale

0.618

High

1317413

IRAK3
Interleukin-1 receptor-associated kinase 3

1

19

Small-scale

0.618

High

1298412

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

20

Small-scale

0.575

High

1341613

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

2

Small-scale

0.489

High

1341612

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

2

Small-scale

0.481

High

1223815

RAGE
Advanced glycosylation end product-specific receptor

1

1

Small-scale

0.445

High

1283304

WDTC1
WD and tetratricopeptide repeats protein 1

1

2

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025