HitPredict

Interactor 1: BOLA2 (Q9FIC3)
Protein BOLA2
Gene: BOLA2

Interactor 2: GRS17 (Q9ZPH2)
Monothiol glutaredoxin-S17 (AtGrxS17)
Gene: GRXS17

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.849

Property	Details
Experiments	27503603, 21798944, 24203231
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	BolA~Glutaredoxin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006879 - intracellular iron ion homeostasis GO:0051537 - 2 iron, 2 sulfur cluster binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 93 At			1 488
+	At
		1196496 SUFE1_ARATH (6-78): 1.75e-21: 87.8: 32.96		GRS17_ARATH (1-488): 1.18e-147: 432: 100.00
+	Hs
		280471 BOLA2_HUMAN (2-84): 5.97e-29: 100: 45.24		GLRX3_HUMAN (176-487): 5.23e-69: 225: 41.33
+	Hs
		280488 BOLA1_HUMAN (3-84): 2.74e-27: 98.2: 41.57		GLRX3_HUMAN (176-487): 5.23e-69: 225: 41.33
+	At
		1227407 BOLA2_ARATH (1-93): 5.18e-38: 124: 100.00		GRS15_ARATH (95-253): 6.7e-40: 143: 32.93
+	Hs
		1197948 BOLA1_HUMAN (3-84): 2.74e-27: 98.2: 41.57		GLRX5_HUMAN (155-268): 6.63e-43: 151: 44.35
+	At
		1196707 BOLA2_ARATH (1-93): 5.18e-38: 124: 100.00		GRS14_ARATH (108-253): 2.63e-30: 117: 37.67
+	At
		1196493 SUFE1_ARATH (6-78): 1.75e-21: 87.8: 32.96		GRS15_ARATH (95-253): 6.7e-40: 143: 32.93
+	Sc
		763749 BOL3_YEAST (3-75): 3.27e-25: 92.5: 30.14		GLRX5_YEAST (149-265): 4.82e-37: 135: 40.50
+	Ec
		466339 BOLA_ECOLI (1-80): 2.25e-26: 95.2: 36.78		GLRX4_ECOLI (155-264): 4.19e-35: 128: 37.27
+	Sp
		145312 YETB_SCHPO (1-80): 1.79e-31: 107: 48.75		GLRX4_SCHPO (176-380): 1.57e-28: 114: 30.56
+	Dm
		53878 A1Z933_DROME (4-81): 4.43e-28: 98.6: 43.59		Q8SXQ5_DROME (153-263): 2.76e-31: 119: 40.54
+	At
		1210847 BOLA2_ARATH (1-93): 5.18e-38: 124: 100.00		GRS16_ARATH (64-250): 5.19e-20: 92.2: 26.84
+	Ec
		465348 IBAG_ECOLI (2-84): 9.21e-24: 87.8: 29.41		GLRX4_ECOLI (155-264): 4.19e-35: 128: 37.27
+	Dm
		53885 A1Z933_DROME (4-81): 4.43e-28: 98.6: 43.59		Q9VJZ6_DROME (154-380): 4.12e-26: 107: 29.61
+	At
		1196490 SUFE1_ARATH (6-78): 1.75e-21: 87.8: 32.96		GRS14_ARATH (108-253): 2.63e-30: 117: 37.67
+	Sc
		697322 BOL2_YEAST (2-81): 1.15e-25: 93.6: 41.98		GLRX4_YEAST (296-479): 2.53e-26: 108: 33.02
+	Sc
		697320 BOL3_YEAST (3-75): 3.27e-25: 92.5: 30.14		GLRX4_YEAST (296-479): 2.53e-26: 108: 33.02
+	Sc
		858951 BOL2_YEAST (2-81): 1.15e-25: 93.6: 41.98		GLRX3_YEAST (146-373): 2.18e-25: 106: 27.24
+	Sc
		763750 BOL3_YEAST (3-75): 3.27e-25: 92.5: 30.14		GLRX3_YEAST (146-373): 2.18e-25: 106: 27.24
+	At
		1196492 SUFE1_ARATH (6-78): 1.75e-21: 87.8: 32.96		GRS16_ARATH (64-250): 5.19e-20: 92.2: 26.84