Protein: NUP49
Nucleoporin NUP49/NSP49 (Nuclear pore protein NUP49/NSP49)

Gene: NUP49
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: Q02199

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003723 - RNA binding
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

877969

NUP57
Nucleoporin NUP57

19

19

Small-scale

0.765

High

577331

NSP1
Nucleoporin NSP1

15

19

Small-scale

0.762

High

756652

NIC96
Nucleoporin NIC96

12

15

Small-scale

0.755

High

914988

NUP84
Nucleoporin NUP84

6

13

Small-scale

0.723

High

1035273

IMB1
Importin subunit beta-1

5

20

Small-scale

0.713

High

858316

NUP85
Nucleoporin NUP85

4

6

Small-scale

0.680

High

1035260

NUP49
Nucleoporin NUP49/NSP49

3

18

Small-scale

0.672

High

722181

XPO1
Exportin-1

3

20

Small-scale

0.648

High

1035263

NU116
Nucleoporin NUP116/NSP116

3

19

Small-scale

0.641

High

782546

NU133
Nucleoporin NUP133

3

9

High-throughput

0.640

High

886198

NU145
Nucleoporin NUP145

3

17

Small-scale

0.636

High

738498

NUP2
Nucleoporin NUP2

2

20

High-throughput

0.614

High

734715

IMB3
Importin subunit beta-3

2

20

Small-scale

0.595

High

1035262

NU100
Nucleoporin NUP100/NSP100

2

19

Small-scale

0.595

High

776537

NU120
Nucleoporin NUP120

2

5

Small-scale

0.584

High

795157

NU170
Nucleoporin NUP170

2

18

High-throughput

0.584

High

1035261

MLP1
Protein MLP1

2

20

High-throughput

0.584

High

527462

HSP72
Heat shock protein SSA2

3

13

High-throughput

0.578

High

823494

NUP82
Nucleoporin NUP82

2

5

Small-scale

0.576

High

795499

ATG8
Autophagy-related protein 8

2

11

Small-scale

0.533

High

1025162

SEN1
Helicase SEN1

1

2

Small-scale

0.508

High

618358

CDC42
Cell division control protein 42

1

3

Small-scale

0.501

High

886171

NUP42
Nucleoporin NUP42

1

19

Small-scale

0.501

High

1035268

ARX1
Probable metalloprotease ARX1

1

4

Small-scale

0.501

High

925315

COG6
Conserved oligomeric Golgi complex subunit 6

1

1

High-throughput

0.494

High

796112

IMB2
Importin subunit beta-2

1

20

Small-scale

0.481

High

1035276

MTR10
mRNA transport regulator MTR10

1

20

Small-scale

0.481

High

403626

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

3

High-throughput

0.479

High

524884

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.479

High

634267

NUP1
Nucleoporin NUP1

1

19

High-throughput

0.479

High

738903

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

5

High-throughput

0.479

High

813424

PO152
Nucleoporin POM152

1

5

High-throughput

0.479

High

817813

NU157
Nucleoporin NUP157

1

18

High-throughput

0.479

High

817931

IMB4
Importin subunit beta-4

1

20

High-throughput

0.479

High

824770

MLP2
Protein MLP2

1

20

High-throughput

0.479

High

825168

NU159
Nucleoporin NUP159

1

19

High-throughput

0.479

High

858347

SAC3
Nuclear mRNA export protein SAC3

1

4

High-throughput

0.479

High

864641

NU192
Nucleoporin NUP192

1

15

High-throughput

0.479

High

893285

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

7

High-throughput

0.479

High

912744

NU188
Nucleoporin NUP188

1

5

High-throughput

0.479

High

915392

MSN5
Protein MSN5

1

20

High-throughput

0.479

High

1035264

IMA1
Importin subunit alpha

1

12

High-throughput

0.479

High

1035265

KA120
Importin beta-like protein KAP120

1

20

High-throughput

0.479

High

692421

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

High-throughput

0.457

High

793193

AKL1
Serine/threonine-protein kinase AKL1

1

3

High-throughput

0.457

High

864419

IKS1
Probable serine/threonine-protein kinase IKS1

1

2

High-throughput

0.457

High

1035272

NUP59
Nucleoporin ASM4

1

8

Small-scale

0.457

High

438219

CDC37
Hsp90 co-chaperone Cdc37

1

1

Small-scale

0.439

High

545948

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.437

High

748509

SC61A
Protein transport protein SEC61

1

2

High-throughput

0.437

High

752629

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.437

High

963657

H3
Histone H3

1

2

High-throughput

0.437

High

1035267

RMT2
Protein arginine N-methyltransferase 2

1

3

Small-scale

0.437

High

1035275

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.437

High

1035274

SP382
Pre-mRNA-splicing factor SPP382

1

1

High-throughput

0.417

High

453751

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.407

High

651979

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

5

High-throughput

0.407

High

797123

CENPL
Inner kinetochore subunit IML3

1

1

High-throughput

0.407

High

819550

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.407

High

1035270

SPC24
Kinetochore protein SPC24

1

2

High-throughput

0.407

High

661553

PSA2
Proteasome subunit alpha type-2

2

0

Small-scale

0.317

High

871018

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

1

0

High-throughput

0.282

High

814087

MTW1
Kinetochore-associated protein MTW1

1

0

High-throughput

0.265

Low

811655

CIN4
GTP-binding protein CIN4

1

0

Small-scale

0.251

Low

826757

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

1035266

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.249

Low

1035269

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

1035271

DFG5
Mannan endo-1,6-alpha-mannosidase DFG5

1

0

High-throughput

0.249

Low

598906

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025