Protein: NIC96
Nucleoporin NIC96 (96 kDa nucleoporin-interacting component) (Nuclear pore protein NIC96)

Gene: NIC96
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P34077

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0006606 - protein import into nucleus
GO:0006913 - nucleocytoplasmic transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

756643

NU188
Nucleoporin NUP188

8

1

Small-scale

0.967

High

756637

NU192
Nucleoporin NUP192

5

3

Small-scale

0.932

High

756644

NUP84
Nucleoporin NUP84

6

1

Small-scale

0.931

High

756618

NU170
Nucleoporin NUP170

4

4

Small-scale

0.873

High

756638

NUP57
Nucleoporin NUP57

15

17

Small-scale

0.761

High

577288

NSP1
Nucleoporin NSP1

12

16

Small-scale

0.758

High

756652

NUP49
Nucleoporin NUP49/NSP49

12

15

Small-scale

0.755

High

756617

NU133
Nucleoporin NUP133

2

1

High-throughput

0.754

High

756626

NU157
Nucleoporin NUP157

2

4

High-throughput

0.754

High

738525

NDC1
Nucleoporin NDC1

2

0

High-throughput

0.753

High

756658

NUP53
Nucleoporin NUP53

9

1

Small-scale

0.749

High

756655

NU116
Nucleoporin NUP116/NSP116

4

17

Small-scale

0.680

High

756654

NU100
Nucleoporin NUP100/NSP100

3

17

Small-scale

0.667

High

756624

PO152
Nucleoporin POM152

4

0

Small-scale

0.653

High

756630

MLP2
Protein MLP2

3

3

Small-scale

0.640

High

756653

MLP1
Protein MLP1

3

4

High-throughput

0.640

High

756674

MEX67
mRNA export factor MEX67

2

1

High-throughput

0.584

High

734649

IMB3
Importin subunit beta-3

1

3

Small-scale

0.578

High

756663

NUP59
Nucleoporin ASM4

2

1

Small-scale

0.576

High

756628

IMB4
Importin subunit beta-4

2

3

Small-scale

0.571

High

738806

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

0

Small-scale

0.559

High

738460

NUP2
Nucleoporin NUP2

1

6

High-throughput

0.541

High

756664

IMB1
Importin subunit beta-1

1

4

Small-scale

0.501

High

526317

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.489

High

756645

MSN5
Protein MSN5

1

1

Small-scale

0.481

High

756616

NU120
Nucleoporin NUP120

1

0

Small-scale

0.480

High

634218

NUP1
Nucleoporin NUP1

1

6

High-throughput

0.479

High

756627

GLE2
mRNA export factor GLE2

1

3

High-throughput

0.479

High

756631

NU159
Nucleoporin NUP159

1

8

High-throughput

0.479

High

756639

NUP42
Nucleoporin NUP42

1

9

High-throughput

0.479

High

756640

NU145
Nucleoporin NUP145

1

19

High-throughput

0.479

High

756641

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.479

High

756646

SEH1
Nucleoporin SEH1

1

4

High-throughput

0.479

High

756657

HEH2
Inner nuclear membrane protein HEH2

1

2

Small-scale

0.479

High

756671

GLE1
mRNA export factor GLE1

1

1

High-throughput

0.479

High

548685

RNA1
Ran GTPase-activating protein 1

1

0

High-throughput

0.460

High

756668

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

554331

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.458

High

756622

BRL1
Nucleus export protein BRL1

1

0

Small-scale

0.458

High

756629

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.458

High

756634

NUP85
Nucleoporin NUP85

1

0

High-throughput

0.458

High

756673

POM34
Nucleoporin POM34

1

0

High-throughput

0.458

High

756649

YG3A
Uncharacterized protein YGR130C

1

3

High-throughput

0.439

High

756667

SLK19
Kinetochore protein SLK19

1

1

High-throughput

0.439

High

706683

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

756623

NMD3
60S ribosomal export protein NMD3

1

0

Small-scale

0.426

High

756650

JJJ1
J protein JJJ1

1

0

High-throughput

0.426

High

735987

SP110
Spindle pole body component 110

1

1

Small-scale

0.407

High

756651

CDC14
Tyrosine-protein phosphatase CDC14

1

3

High-throughput

0.407

High

756619

ATG8
Autophagy-related protein 8

2

0

Small-scale

0.305

High

656413

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.279

Low

756642

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.265

Low

756648

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.265

Low

460327

SYV
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

756615

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

756621

ETP1
RING finger protein ETP1

1

0

High-throughput

0.251

Low

756633

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.251

Low

756672

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low

434977

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

550644

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.249

Low

726907

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

739944

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.249

Low

756614

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

756632

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

756635

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.249

Low

756647

SHY1
Cytochrome oxidase assembly protein SHY1

1

0

Small-scale

0.249

Low

756656

ESP1
Separin

1

0

High-throughput

0.249

Low

756659

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

756661

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

756662

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

756665

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

756669

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.249

Low

756670

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

756666

SDO1
Ribosome maturation protein SDO1

1

0

High-throughput

0.238

Low

381052

H2B1
Histone H2B.1

1

0

High-throughput

0.232

Low

453524

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

651918

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.232

Low

686886

BUB2
Mitotic check point protein BUB2

1

0

High-throughput

0.232

Low

756620

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.232

Low

756625

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.232

Low

756636

STU2
Protein STU2

1

0

High-throughput

0.232

Low

756660

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025