Interactor 1: APC1 (Q9H1A4)
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)
Gene: ANAPC1

Interactor 2: ANC2 (Q9UJX6)
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)
Gene: ANAPC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 11076961, 10922056, 12956947, 34079125, 35271311, 20360068
Identification Methods biochemical, affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle
GO:0007346 - regulation of mitotic cell cycle
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1944
Hs

1 822
+ Hs
+ At
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024