HitPredict

Interactor 1: CLC4M (Q9H2X3)
C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299)
Gene: CLEC4M

Interactor 2: CD209 (Q9NNX6)
CD209 antigen (C-type lectin domain family 4 member L) (Dendritic cell-specific ICAM-3-grabbing non-integrin 1) (DC-SIGN) (DC-SIGN1) (CD antigen CD209)
Gene: CD209

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 11384997
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Lectin_C~Lectin_C
Common GO terms GO:0001618 - virus receptor activity
GO:0002250 - adaptive immune response
GO:0005537 - D-mannose binding
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
and 20 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 399
Hs

1 404
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024