HitPredict

Interactor 1: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Interactor 2: SEP11 (Q9NVA2)
Septin-11
Gene: SEPTIN11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015630 - microtubule cytoskeleton
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 429
+	Hs
		1049012 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT6_HUMAN (2-428): 0: 575: 82.01
+	Hs
		1267802 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT8_HUMAN (2-427): 0: 571: 79.02
+	Hs
		1330295 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEP10_HUMAN (11-428): 0: 569: 74.40
+	Hs
		1172584 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEP14_HUMAN (8-425): 0: 534: 64.12
+	Hs
		1080980 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT7_HUMAN (7-428): 0: 529: 39.91
+	Hs
		198202 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT4_HUMAN (21-354): 8.19e-169: 484: 39.33
+	Hs
		1305898 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT5_HUMAN (20-354): 2.08e-162: 463: 39.71
+	Hs
		1063182 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT2_HUMAN (5-350): 5.54e-160: 457: 38.87
+	Hs
		1330298 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT9_HUMAN (6-316): 5.11e-152: 445: 39.50
+	Hs
		1330297 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		SEPT3_HUMAN (8-306): 1.27e-152: 438: 43.32
+	Hs
		1049020 BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21		SEPT6_HUMAN (2-428): 0: 575: 82.01
+	Hs
		960668 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		SEP10_HUMAN (11-428): 0: 569: 74.40
+	Hs
		150125 BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86		SEPT6_HUMAN (2-428): 0: 575: 82.01
+	Hs
		1080995 BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21		SEPT7_HUMAN (7-428): 0: 529: 39.91
+	Hs
		150127 BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86		SEPT7_HUMAN (7-428): 0: 529: 39.91