HitPredict

Interactor 1: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Interactor 2: ARI1 (Q9Y4X5)
E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (H7-AP2) (HHARI) (Monocyte protein 6) (MOP-6) (Protein ariadne-1 homolog) (ARI-1) (UbcH7-binding protein) (UbcM4-interacting protein) (Ubiquitin-conjugating enzyme E2-binding protein 1)
Gene: ARIH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 27565346, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016604 - nuclear body
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 914 Hs			1 557
+	Hs
		228722 ECT2_HUMAN (1-914): 0: 886: 100.00		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10
+	Hs
		1333781 ECT2_HUMAN (1-914): 0: 886: 100.00		RNF14_HUMAN (180-399): 3.26e-54: 192: 24.81
+	Hs
		855831 VAV2_HUMAN (386-707): 7.77e-69: 248: 18.94		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		1273261 ARHG2_HUMAN (249-775): 2e-83: 291: 15.02		RNF31_HUMAN (127-397): 1.98e-58: 212: 19.22
+	Hs
		227424 ARHG7_HUMAN (309-913): 4.64e-90: 305: 11.83		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10
+	Hs
		227296 AKP13_HUMAN (274-912): 7.43e-83: 295: 13.83		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10
+	Hs
		228266 ARHG2_HUMAN (249-775): 2e-83: 291: 15.02		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10
+	Hs
		228391 FGD4_HUMAN (312-858): 1.12e-81: 281: 18.53		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10
+	Hs
		164146 ARHGA_HUMAN (436-704): 1.71e-23: 109: 29.33		RNF31_HUMAN (127-397): 1.98e-58: 212: 19.22
+	Hs
		92352 E9PB39_HUMAN (436-657): 9.31e-23: 103: 30.60		RNF31_HUMAN (127-397): 1.98e-58: 212: 19.22