HitPredict

Interactor 1: M2K5 (Q8RXG3)
Mitogen-activated protein kinase kinase 5 (AtMAP2Kalpha) (AtMEK5) (AtMKK5) (MAP kinase kinase 5) (EC 2.7.12.2)
Gene: MKK5

Interactor 2: GPLPC (Q9LV28)
Small ribosomal subunit protein RACK1x (Guanine nucleotide-binding protein subunit beta-like protein C) (Receptor for activated C kinase 1C)
Gene: RACK1C

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	25731164
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 348 At			1 326
+	At
		305992 M2K4_ARATH (1-337): 8.05e-129: 374: 78.04		GPLPC_ARATH (1-326): 7.86e-107: 316: 100.00
+	At
		305989 M2K4_ARATH (1-337): 8.05e-129: 374: 78.04		GPLPB_ARATH (1-326): 5.16e-105: 311: 92.95
+	At
		1342154 M2K5_ARATH (1-348): 4.77e-128: 372: 100.00		GPLPB_ARATH (1-326): 5.16e-105: 311: 92.95
+	At
		200906 M2K4_ARATH (1-337): 8.05e-129: 374: 78.04		GBLPA_ARATH (1-326): 1.59e-102: 305: 87.16
+	At
		201009 M2K5_ARATH (1-348): 4.77e-128: 372: 100.00		GBLPA_ARATH (1-326): 1.59e-102: 305: 87.16
+	Dm
		198149 AKT1_DROME (26-347): 1.51e-124: 372: 20.96		GBLP_DROME (1-324): 1.1e-98: 295: 61.85
+	At
		201059 M2K9_ARATH (35-326): 3.26e-114: 335: 51.34		GBLPA_ARATH (1-326): 1.59e-102: 305: 87.16
+	Hs
		728368 AKT1_HUMAN (10-347): 2.09e-126: 372: 21.37		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	Hs
		667616 CDK2_HUMAN (67-335): 1.64e-111: 328: 29.93		LIS1_HUMAN (101-325): 2.01e-55: 187: 20.61
+	Hs
		1097718 STK3_HUMAN (47-338): 3.07e-113: 339: 31.33		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	Hs
		170270 AURKA_HUMAN (3-333): 2.65e-113: 336: 27.54		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	At
		1182690 KIN10_ARATH (55-341): 7.59e-129: 380: 28.33		PRL1_ARATH (183-325): 2.36e-23: 101: 23.45
+	Hs
		667968 CDK2_HUMAN (67-335): 1.64e-111: 328: 29.93		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	At
		1020115 KIN11_ARATH (69-341): 2.06e-126: 373: 28.32		PRL1_ARATH (183-325): 2.36e-23: 101: 23.45
+	Hs
		992693 KPCE_HUMAN (5-346): 1.57e-123: 373: 19.61		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95
+	Hs
		667751 CDK2_HUMAN (67-335): 1.64e-111: 328: 29.93		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95
+	Hs
		783546 MP2K2_HUMAN (69-328): 2.25e-40: 148: 32.69		WDR5_HUMAN (47-325): 6.19e-82: 253: 26.95
+	Hs
		1038336 MP2K1_HUMAN (69-328): 2.24e-45: 161: 34.10		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	Hs
		992694 MP2K1_HUMAN (69-328): 2.24e-45: 161: 34.10		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95
+	Hs
		993059 M3K4_HUMAN (71-325): 4.55e-39: 149: 35.88		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95