HitPredict

Interactor 1: M2K4 (O80397)
Mitogen-activated protein kinase kinase 4 (AtMKK4) (MAP kinase kinase 4) (EC 2.7.12.2)
Gene: MKK4

Interactor 2: GPLPC (Q9LV28)
Small ribosomal subunit protein RACK1x (Guanine nucleotide-binding protein subunit beta-like protein C) (Receptor for activated C kinase 1C)
Gene: RACK1C

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	25731164
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 At			1 326
+	At
		1342155 M2K5_ARATH (1-362): 1.14e-125: 366: 77.90		GPLPC_ARATH (1-326): 7.86e-107: 316: 100.00
+	At
		305989 M2K4_ARATH (1-350): 1.18e-125: 367: 100.00		GPLPB_ARATH (1-326): 5.16e-105: 311: 92.95
+	At
		1342154 M2K5_ARATH (1-362): 1.14e-125: 366: 77.90		GPLPB_ARATH (1-326): 5.16e-105: 311: 92.95
+	At
		200906 M2K4_ARATH (1-350): 1.18e-125: 367: 100.00		GBLPA_ARATH (1-326): 1.59e-102: 305: 87.16
+	Dm
		198149 AKT1_DROME (54-365): 6.22e-126: 376: 22.60		GBLP_DROME (1-324): 1.1e-98: 295: 61.85
+	At
		201009 M2K5_ARATH (1-362): 1.14e-125: 366: 77.90		GBLPA_ARATH (1-326): 1.59e-102: 305: 87.16
+	At
		201059 M2K9_ARATH (78-337): 4.11e-108: 320: 51.89		GBLPA_ARATH (1-326): 1.59e-102: 305: 87.16
+	Mm
		591065 KPCE_MOUSE (4-365): 5.63e-125: 377: 19.63		FBXW7_MOUSE (133-325): 3.47e-40: 151: 19.91
+	Hs
		728368 AKT1_HUMAN (22-365): 1.95e-127: 375: 22.19		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	At
		1182690 KIN10_ARATH (64-347): 8.4e-129: 380: 27.59		PRL1_ARATH (183-325): 2.36e-23: 101: 23.45
+	At
		1020115 KIN11_ARATH (78-342): 4.52e-126: 373: 27.68		PRL1_ARATH (183-325): 2.36e-23: 101: 23.45
+	Hs
		1097718 STK3_HUMAN (54-339): 1.25e-105: 320: 30.72		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	Hs
		170270 AURKA_HUMAN (3-342): 3.33e-106: 319: 26.06		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	Hs
		992693 KPCE_HUMAN (4-365): 1.1e-124: 377: 19.90		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95
+	Hs
		783546 MP2K2_HUMAN (78-337): 3.38e-45: 161: 34.95		WDR5_HUMAN (47-325): 6.19e-82: 253: 26.95
+	Hs
		1038336 MP2K1_HUMAN (78-341): 3.04e-47: 166: 34.95		FBXW7_HUMAN (133-325): 9.29e-40: 150: 19.91
+	Hs
		992694 MP2K1_HUMAN (78-341): 3.04e-47: 166: 34.95		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95
+	Hs
		783553 MP2K2_HUMAN (78-337): 3.38e-45: 161: 34.95		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95
+	Hs
		858621 MP2K3_HUMAN (66-333): 1.85e-38: 142: 33.33		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95
+	Hs
		993059 M3K4_HUMAN (81-334): 1.9e-36: 142: 35.25		RACK1_HUMAN (12-138): 7.93e-16: 78.5: 16.95