HitPredict

Interactor 1: DPOE3 (Q9NRF9)
DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)
Gene: POLE3

Interactor 2: CHRC1 (Q9NRG0)
Chromatin accessibility complex protein 1 (CHRAC-1) (Chromatin accessibility complex 15 kDa protein) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15)
Gene: CHRAC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 32296183, 25416956, 21516116, 10880450, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CBFD_NFYB_HMF~CBFD_NFYB_HMF
Common GO terms GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005721 - pericentric heterochromatin
GO:0006261 - DNA-templated DNA replication
GO:0006275 - regulation of DNA replication
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 147
Hs

1 131
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024