HitPredict

Interactor 1: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 15509568, 30700555, 33508099, 35355521, 21396873, 21549715, 24672041, 25023518
Identification Methods enzymatic study, pull down, x-ray crystallography, two hybrid, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000403 - Y-form DNA binding
GO:0003684 - damaged DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 18 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 495
Hs

1 495
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024