HitPredict

Interactor 1: Q8T5S9 (Q8T5S9)
GH12103p (Menage a trois, isoform B) (RH70415p) (Skiff)
Gene: metro

Interactor 2: Q9VBY7 (Q9VBY7)
Protein lin-7 homolog
Gene: veli

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	14605208, unassigned1513
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, L27~L27, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0005911 - cell-cell junction GO:0008582 - regulation of synaptic assembly at neuromuscular junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Dm			1 195
+	Dm
		122386 M9PJD0_DROME (132-556): 7.75e-162: 507: 37.89		Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00
+	Dm
		54269 A1Z8G0_DROME (1-556): 4.1e-166: 486: 93.28		Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00
+	Hs
		1450016 PALS2_HUMAN (16-556): 1.14e-150: 445: 33.87		LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00
+	Hs
		1437597 PALS2_HUMAN (16-556): 1.14e-150: 445: 33.87		LIN7B_HUMAN (1-195): 7.6e-52: 167: 77.44
+	Hs
		167723 PALS2_HUMAN (16-556): 1.14e-150: 445: 33.87		LIN7A_HUMAN (6-194): 1.48e-49: 162: 77.78
+	Hs
		1122734 MPP2_HUMAN (9-556): 7.99e-146: 434: 31.65		LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00
+	Hs
		1212215 MPP7_HUMAN (4-556): 6.57e-146: 434: 38.06		LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00
+	Hs
		1122731 MPP2_HUMAN (9-556): 7.99e-146: 434: 31.65		LIN7B_HUMAN (1-195): 7.6e-52: 167: 77.44
+	Hs
		1212210 MPP7_HUMAN (4-556): 6.57e-146: 434: 38.06		LIN7B_HUMAN (1-195): 7.6e-52: 167: 77.44
+	Hs
		167699 MPP2_HUMAN (9-556): 7.99e-146: 434: 31.65		LIN7A_HUMAN (6-194): 1.48e-49: 162: 77.78
+	Hs
		167705 MPP7_HUMAN (4-556): 6.57e-146: 434: 38.06		LIN7A_HUMAN (6-194): 1.48e-49: 162: 77.78
+	Hs
		167670 CSKP_HUMAN (3-556): 1.21e-128: 400: 28.32		LIN7A_HUMAN (6-194): 1.48e-49: 162: 77.78
+	Dm
		54265 A1Z8G0_DROME (1-556): 4.1e-166: 486: 93.28		DLG1_DROME (94-175): 1.78e-14: 72.8: 37.93
+	Mm
		1223777 MPP2_MOUSE (9-556): 2.2e-146: 434: 32.46		DLG4_MOUSE (41-181): 2.63e-26: 107: 26.03
+	Hs
		1091491 MPP2_HUMAN (9-556): 7.99e-146: 434: 31.65		DLG1_HUMAN (60-181): 1.06e-25: 105: 30.71
+	Hs
		168683 CSKP_HUMAN (3-556): 1.21e-128: 400: 28.32		SNTB2_HUMAN (63-179): 2.85e-31: 120: 35.83
+	Ce
		111226 Q17549_CAEEL (161-554): 1.06e-142: 429: 31.79		DLG1_CAEEL (39-174): 9.11e-20: 88.2: 21.83
+	Hs
		168670 CSKP_HUMAN (3-556): 1.21e-128: 400: 28.32		DLG4_HUMAN (41-181): 3.38e-26: 106: 26.03
+	Hs
		168680 CSKP_HUMAN (3-556): 1.21e-128: 400: 28.32		DLG1_HUMAN (60-181): 1.06e-25: 105: 30.71
+	Hs
		1212202 MPP7_HUMAN (4-556): 6.57e-146: 434: 38.06		SNX27_HUMAN (91-175): 7.33e-12: 65.1: 38.14