HitPredict

Interactor 1: TMOD2 (Q9NZR1)
Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Gene: TMOD2

Interactor 2: SCIN (Q9Y6U3)
Scinderin (Adseverin)
Gene: SCIN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Gelsolin~Tropomodulin
Common GO terms	GO:0003779 - actin binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 715
+	Hs
		1348584 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		657569 TMOD1_HUMAN (3-346): 2.23e-115: 340: 59.71		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		414088 TMOD2_HUMAN (1-351): 3.19e-129: 375: 100.00		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		414084 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413834 TMOD1_HUMAN (3-346): 2.23e-115: 340: 59.71		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		1023245 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		657487 TMOD1_HUMAN (3-346): 2.23e-115: 340: 59.71		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		1023247 TMOD4_HUMAN (4-345): 1.16e-114: 338: 54.23		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		313893 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		SVIL_HUMAN (21-347): 1.62e-31: 134: 21.73
+	Hs
		260677 TMOD2_HUMAN (1-351): 3.19e-129: 375: 100.00		AVIL_HUMAN (44-539): 1.91e-23: 108: 18.37
+	Hs
		313758 TMOD1_HUMAN (3-346): 2.23e-115: 340: 59.71		SVIL_HUMAN (21-347): 1.62e-31: 134: 21.73
+	Mm
		1246902 NLRP3_MOUSE (175-335): 1.18e-28: 119: 16.36		FLII_MOUSE (18-352): 1.3e-28: 125: 17.95