Protein: ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-)

Gene: ATS12, ADAMTS12
Organism: Homo sapiens
Interactions: 75
UniProt ID: P58397

Gene Ontology (top 5):
GO:0002062 - chondrocyte differentiation
GO:0004222 - metalloendopeptidase activity
GO:0005576 - extracellular region
GO:0006508 - proteolysis
GO:0007160 - cell-matrix adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

287547

LRP6
Low-density lipoprotein receptor-related protein 6

1

4

High-throughput

0.691

High

648475

FGFR4
Fibroblast growth factor receptor 4

1

5

High-throughput

0.691

High

650110

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.691

High

946268

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

11

High-throughput

0.691

High

333744

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

3

1

High-throughput

0.609

High

648340

USF1
Upstream stimulatory factor 1

3

5

High-throughput

0.609

High

946241

USF2
Upstream stimulatory factor 2

3

5

High-throughput

0.609

High

946249

UBR1
E3 ubiquitin-protein ligase UBR1

3

2

High-throughput

0.609

High

888495

COMP
Cartilage oligomeric matrix protein

2

13

Small-scale

0.601

High

369645

A2MG
Alpha-2-macroglobulin

1

2

Small-scale

0.575

High

946269

PSG8
Pregnancy-specific beta-1-glycoprotein 8

1

1

High-throughput

0.575

High

946230

MYL6
Myosin light polypeptide 6

2

1

High-throughput

0.573

High

946239

TRI14
Tripartite motif-containing protein 14

2

3

High-throughput

0.553

High

350698

NOE2
Noelin-2

1

2

High-throughput

0.536

High

582322

ARSA
Arylsulfatase A

1

3

High-throughput

0.536

High

946244

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

1

High-throughput

0.536

High

946248

MISP
Mitotic interactor and substrate of PLK1

1

1

High-throughput

0.536

High

946254

ARSG
Arylsulfatase G

1

3

High-throughput

0.536

High

946260

TBB1
Tubulin beta-1 chain

1

6

High-throughput

0.536

High

618183

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

0

High-throughput

0.513

High

946234

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.513

High

946255

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

946256

NAR5
Ecto-ADP-ribosyltransferase 5

1

0

High-throughput

0.513

High

946271

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.513

High

946247

P3H3
Prolyl 3-hydroxylase 3

1

2

High-throughput

0.489

High

946257

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

2

High-throughput

0.489

High

946259

CSTN3
Calsyntenin-3

1

10

High-throughput

0.489

High

946266

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.489

High

946233

Q05BL1
TP53BP2 protein

1

2

High-throughput

0.470

High

73792

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

7

High-throughput

0.445

High

437657

HEPS
Serine protease hepsin

1

11

High-throughput

0.445

High

505815

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

6

High-throughput

0.445

High

570657

EDN3
Endothelin-3

1

2

High-throughput

0.445

High

663540

CMA1
Chymase

1

20

High-throughput

0.445

High

946232

NOTC2
Neurogenic locus notch homolog protein 2

1

16

High-throughput

0.445

High

946235

DNJC3
DnaJ homolog subfamily C member 3

1

2

High-throughput

0.445

High

946246

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

4

High-throughput

0.445

High

946251

LYPD1
Ly6/PLAUR domain-containing protein 1

1

3

High-throughput

0.445

High

946252

CA054
Uncharacterized protein C1orf54

1

3

High-throughput

0.445

High

946253

PATE1
Prostate and testis expressed protein 1

1

2

High-throughput

0.445

High

946261

FBX6
F-box only protein 6

1

9

High-throughput

0.445

High

946267

FBX2
F-box only protein 2

1

9

High-throughput

0.445

High

946270

CLC11
C-type lectin domain family 11 member A

1

5

High-throughput

0.445

High

946272

NTNG1
Netrin-G1

1

2

High-throughput

0.445

High

946273

PRG3
Proteoglycan 3

1

10

High-throughput

0.445

High

946238

ASPP2
Apoptosis-stimulating of p53 protein 2

1

2

High-throughput

0.439

High

256813

H2B1K
Histone H2B type 1-K

1

9

High-throughput

0.437

High

449694

H2B1J
Histone H2B type 1-J

1

9

High-throughput

0.437

High

571663

HCLS1
Hematopoietic lineage cell-specific protein

1

8

High-throughput

0.437

High

659878

H2B1O
Histone H2B type 1-O

1

9

High-throughput

0.437

High

943335

H2BFS
Histone H2B type F-S

1

9

High-throughput

0.437

High

946229

H2B1D
Histone H2B type 1-D

1

9

High-throughput

0.437

High

946240

EEA1
Early endosome antigen 1

1

1

High-throughput

0.437

High

946242

H2B2F
Histone H2B type 2-F

1

9

High-throughput

0.437

High

946258

H2B1N
Histone H2B type 1-N

1

9

High-throughput

0.437

High

946264

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

1

High-throughput

0.437

High

942174

WNT4
Protein Wnt-4

1

0

High-throughput

0.426

High

170722

CLGN
Calmegin

1

5

High-throughput

0.407

High

449598

KLK1
Kallikrein-1

1

18

High-throughput

0.407

High

945889

INHBE
Inhibin beta E chain

1

6

High-throughput

0.407

High

776944

PPM1A
Protein phosphatase 1A

3

0

High-throughput

0.347

High

946263

SNRK
SNF-related serine/threonine-protein kinase

3

0

High-throughput

0.347

High

946231

SP3
Transcription factor Sp3

2

0

High-throughput

0.318

High

799823

COIL
Coilin

2

0

High-throughput

0.316

High

946250

IHO1
Interactor of HORMAD1 protein 1

2

0

High-throughput

0.316

High

893782

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

946237

SQSTM
Sequestosome-1

1

0

High-throughput

0.279

Low

946243

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.279

Low

946245

RUFY3
Protein RUFY3

1

0

High-throughput

0.279

Low

946265

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.279

Low

76269

B4DJ51
Calmodulin 1

1

0

High-throughput

0.268

Low

760883

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

775738

CYLC1
Cylicin-1

1

0

High-throughput

0.249

Low

946236

CD5R2
Cyclin-dependent kinase 5 activator 2

1

0

High-throughput

0.249

Low

946262

DUOX2
Dual oxidase 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025