Protein: ADA12
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)

Gene: ADA12, ADAM12
Organism: Homo sapiens
Interactions: 60
UniProt ID: O43184

Gene Ontology (top 5):
GO:0004222 - metalloendopeptidase activity
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

209878

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

5

Small-scale

0.629

High

209873

IBP3
Insulin-like growth factor-binding protein 3

2

3

Small-scale

0.625

High

209862

SPY1
Protein sprouty homolog 1

2

1

High-throughput

0.615

High

209863

MABP1
Mitogen-activated protein kinase-binding protein 1

2

2

High-throughput

0.606

High

209892

S15A2
Solute carrier family 15 member 2

2

3

High-throughput

0.606

High

209900

ATL4
ADAMTS-like protein 4

2

10

High-throughput

0.606

High

209913

ESM1
Endothelial cell-specific molecule 1

2

0

High-throughput

0.580

High

209864

FSTL3
Follistatin-related protein 3

1

5

Small-scale

0.573

High

209915

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

20

Small-scale

0.573

High

209880

ACTN2
Alpha-actinin-2

1

1

Small-scale

0.561

High

209877

KRA59
Keratin-associated protein 5-9

2

10

High-throughput

0.553

High

209884

KR122
Keratin-associated protein 12-2

2

7

High-throughput

0.553

High

209885

KR108
Keratin-associated protein 10-8

2

9

High-throughput

0.553

High

209887

KRT83
Keratin, type II cuticular Hb3

2

1

High-throughput

0.553

High

209888

KRA11
Keratin-associated protein 1-1

2

9

High-throughput

0.553

High

209897

FHL5
Four and a half LIM domains protein 5

2

4

High-throughput

0.553

High

209903

KRA13
Keratin-associated protein 1-3

2

9

High-throughput

0.553

High

209907

KR412
Keratin-associated protein 4-12

2

9

High-throughput

0.553

High

209908

KRA98
Keratin-associated protein 9-8

2

7

High-throughput

0.553

High

209909

KRA92
Keratin-associated protein 9-2

2

7

High-throughput

0.553

High

209910

KRA32
Keratin-associated protein 3-2

2

1

High-throughput

0.553

High

209911

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

209912

SPY4
Protein sprouty homolog 4

2

1

High-throughput

0.553

High

209869

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.536

High

209870

HCK
Tyrosine-protein kinase HCK

1

20

Small-scale

0.536

High

209872

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.536

High

209890

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.536

High

209867

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.515

High

209875

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

4

High-throughput

0.515

High

209894

SH319
SH3 domain-containing protein 19

1

20

Small-scale

0.515

High

209871

NT2NC
Notch homolog 2 N-terminal-like protein C

1

11

High-throughput

0.515

High

175487

RIMB2
RIMS-binding protein 2

1

11

Small-scale

0.501

High

209868

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.501

High

209874

FST
Follistatin

1

5

Small-scale

0.501

High

209876

IBP5
Insulin-like growth factor-binding protein 5

1

3

Small-scale

0.501

High

209886

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.501

High

209891

ITSN1
Intersectin-1

1

11

Small-scale

0.501

High

209905

SNX33
Sorting nexin-33

1

20

Small-scale

0.501

High

209914

ITSN2
Intersectin-2

1

8

Small-scale

0.501

High

209916

SNX9
Sorting nexin-9

1

20

Small-scale

0.501

High

209904

AHI1
Jouberin

1

2

Small-scale

0.489

High

209865

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.481

High

209901

NT2NA
Notch homolog 2 N-terminal-like protein A

1

10

High-throughput

0.481

High

209861

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

209866

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

17

High-throughput

0.479

High

209881

BASI
Basigin

1

3

High-throughput

0.479

High

209883

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

1

High-throughput

0.479

High

209889

ILK
Scaffold protein ILK

1

10

Small-scale

0.479

High

209899

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

184250

NPHP1
Nephrocystin-1

1

2

Small-scale

0.457

High

209896

SPD2A
SH3 and PX domain-containing protein 2A

1

19

Small-scale

0.457

High

445

NBPFJ
NBPF family member NBPF19

1

2

High-throughput

0.439

High

209882

HXA1
Homeobox protein Hox-A1

3

0

High-throughput

0.348

High

70039

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

209879

OTX1
Homeobox protein OTX1

2

0

High-throughput

0.316

High

209893

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

209895

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.316

High

209898

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.316

High

209902

AP2D
Transcription factor AP-2-delta

2

0

High-throughput

0.316

High

209906

GUCD1
Protein GUCD1

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025