Protein: ADA33
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM 33) (EC 3.4.24.-)

Gene: ADA33, ADAM33
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q9BZ11

Gene Ontology (top 5):
GO:0004222 - metalloendopeptidase activity
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1417128

CLC7A
C-type lectin domain family 7 member A

2

15

High-throughput

0.817

High

1022463

IDD
Integral membrane protein DGCR2/IDD

2

17

High-throughput

0.811

High

1105827

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

2

12

High-throughput

0.811

High

1419457

EGFL7
Epidermal growth factor-like protein 7

2

12

High-throughput

0.726

High

161081

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

12

High-throughput

0.691

High

337282

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

12

High-throughput

0.691

High

1292547

AMGO1
Amphoterin-induced protein 1

1

4

High-throughput

0.691

High

343860

SEM4F
Semaphorin-4F

2

1

High-throughput

0.628

High

520993

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

12

High-throughput

0.628

High

1207896

S27A3
Long-chain fatty acid transport protein 3

2

1

High-throughput

0.628

High

1419447

TM39B
Transmembrane protein 39B

2

2

High-throughput

0.628

High

1419458

FBX2
F-box only protein 2

2

10

High-throughput

0.628

High

1419460

LRP12
Low-density lipoprotein receptor-related protein 12

2

19

High-throughput

0.628

High

1411141

ZNT2
Proton-coupled zinc antiporter SLC30A2

3

4

High-throughput

0.609

High

483965

HMOX1
Heme oxygenase 1

2

0

High-throughput

0.602

High

773972

SOAT1
Sterol O-acyltransferase 1

2

0

High-throughput

0.602

High

934279

BI1
Bax inhibitor 1

2

0

High-throughput

0.602

High

274913

LRP5
Low-density lipoprotein receptor-related protein 5

2

8

High-throughput

0.574

High

287605

LRP6
Low-density lipoprotein receptor-related protein 6

2

8

High-throughput

0.574

High

612116

ITB5
Integrin beta-5

2

12

High-throughput

0.574

High

1293660

DYR2
Dihydrofolate reductase 2, mitochondrial

2

3

High-throughput

0.574

High

1335217

NETO2
Neuropilin and tolloid-like protein 2

2

6

High-throughput

0.574

High

1419448

TOR3A
Torsin-3A

2

2

High-throughput

0.574

High

1419449

ASB7
Ankyrin repeat and SOCS box protein 7

2

3

High-throughput

0.574

High

1419450

ZDHC6
Palmitoyltransferase ZDHHC6

2

2

High-throughput

0.574

High

1419459

NOTC3
Neurogenic locus notch homolog protein 3

2

13

High-throughput

0.574

High

456008

ASGR2
Asialoglycoprotein receptor 2

1

12

High-throughput

0.555

High

1249841

BTNL9
Butyrophilin-like protein 9

1

7

High-throughput

0.555

High

409489

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

12

High-throughput

0.536

High

1292135

ANR46
Ankyrin repeat domain-containing protein 46

1

5

High-throughput

0.536

High

1364142

TM131
Transmembrane protein 131

1

6

High-throughput

0.536

High

1419452

SDF2L
Stromal cell-derived factor 2-like protein 1

1

6

High-throughput

0.536

High

1419461

SPCS1
Signal peptidase complex subunit 1

1

1

High-throughput

0.536

High

1380528

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.513

High

324037

CSTN1
Calsyntenin-1

1

7

High-throughput

0.489

High

1087078

FSTL1
Follistatin-related protein 1

1

5

High-throughput

0.489

High

1419451

DEFM
Peptide deformylase, mitochondrial

1

1

High-throughput

0.489

High

1419455

TM39A
Transmembrane protein 39A

1

2

High-throughput

0.489

High

211948

SPIT1
Kunitz-type protease inhibitor 1

1

9

High-throughput

0.481

High

360105

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.481

High

388453

B3AT
Band 3 anion transport protein

1

2

High-throughput

0.481

High

510100

S35E2
Solute carrier family 35 member E2A

1

1

High-throughput

0.481

High

1242535

GGT6
Glutathione hydrolase 6

1

1

High-throughput

0.481

High

1384346

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

1

2

High-throughput

0.481

High

1400541

TM237
Transmembrane protein 237

1

1

High-throughput

0.481

High

184746

ATX7
Ataxin-7

1

6

High-throughput

0.464

High

1419453

UBQL4
Ubiquilin-4

1

1

High-throughput

0.464

High

380136

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

12

High-throughput

0.445

High

50121

S22AN
Solute carrier family 22 member 23

1

2

High-throughput

0.439

High

213697

AQP9
Aquaporin-9

1

1

High-throughput

0.439

High

220197

TNF14
Tumor necrosis factor ligand superfamily member 14

1

1

High-throughput

0.439

High

302028

NCTR1
Natural cytotoxicity triggering receptor 1

1

3

High-throughput

0.439

High

386193

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.439

High

460280

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

1

High-throughput

0.439

High

553411

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

1

3

High-throughput

0.439

High

590341

MUC1
Mucin-1

1

4

High-throughput

0.439

High

728886

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

1

1

High-throughput

0.439

High

770913

OPRM
Mu-type opioid receptor

1

2

High-throughput

0.439

High

945197

CLD2
Claudin-2

1

2

High-throughput

0.439

High

994954

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

3

High-throughput

0.439

High

1159176

SGCB
Beta-sarcoglycan

1

2

High-throughput

0.439

High

1191795

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

1

High-throughput

0.439

High

1199148

PKHO1
Pleckstrin homology domain-containing family O member 1

1

1

High-throughput

0.439

High

1248379

EPGN
Epigen

1

2

High-throughput

0.439

High

1330281

KI3L3
Killer cell immunoglobulin-like receptor 3DL3

1

3

High-throughput

0.439

High

1347767

STML3
Stomatin-like protein 3

1

2

High-throughput

0.439

High

1415780

T106C
Transmembrane protein 106C

1

7

High-throughput

0.439

High

1419454

TM14B
Transmembrane protein 14B

1

1

High-throughput

0.439

High

505454

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

2

0

High-throughput

0.328

High

1154823

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

2

0

High-throughput

0.328

High

1204896

MKS3
Meckelin

2

0

High-throughput

0.328

High

1217320

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

2

0

High-throughput

0.328

High

1293292

LSR
Lipolysis-stimulated lipoprotein receptor

2

0

High-throughput

0.328

High

1312533

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

2

0

High-throughput

0.328

High

1382880

TTC17
Tetratricopeptide repeat protein 17

2

0

High-throughput

0.328

High

1125872

FZD2
Frizzled-2

1

0

High-throughput

0.279

Low

1419456

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025