HitPredict

Interactor 1: DOK4 (Q8TEW6)
Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5)
Gene: DOK4

Interactor 2: KBTB7 (Q8WVZ9)
Kelch repeat and BTB domain-containing protein 7
Gene: KBTBD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 684
+	Hs
		1290276 DOK4_HUMAN (1-326): 6.85e-138: 395: 100.00		KBTB6_HUMAN (1-674): 7.4e-161: 480: 89.76
+	Hs
		1353339 DOK4_HUMAN (1-326): 6.85e-138: 395: 100.00		KLH20_HUMAN (326-483): 4.96e-23: 106: 18.87
+	Hs
		772525 IRS1_HUMAN (2-302): 1.35e-63: 219: 18.94		KLHL9_HUMAN (312-482): 7.39e-22: 102: 16.57
+	Hs
		772526 IRS1_HUMAN (2-302): 1.35e-63: 219: 18.94		KLH13_HUMAN (326-482): 6.65e-21: 99.6: 16.88