Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
INSR
Insulin receptor |
10 |
20 |
Small-scale |
0.971 | High |
|
|
GRB2
Growth factor receptor-bound protein 2 |
7 |
20 |
Small-scale |
0.963 | High |
|
|
IGF1R
Insulin-like growth factor 1 receptor |
6 |
20 |
Small-scale |
0.929 | High |
|
|
RPTOR
Regulatory-associated protein of mTOR |
3 |
11 |
Small-scale |
0.857 | High |
|
|
JAK2
Tyrosine-protein kinase JAK2 |
3 |
20 |
Small-scale |
0.834 | High |
|
|
JAK1
Tyrosine-protein kinase JAK1 |
3 |
20 |
Small-scale |
0.834 | High |
|
|
MK08
Mitogen-activated protein kinase 8 |
2 |
10 |
Small-scale |
0.807 | High |
|
|
KS6B1
Ribosomal protein S6 kinase beta-1 |
2 |
12 |
Small-scale |
0.799 | High |
|
|
P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha |
36 |
20 |
Small-scale |
0.769 | High |
|
|
AKT1
RAC-alpha serine/threonine-protein kinase |
2 |
10 |
Small-scale |
0.768 | High |
|
|
KPCD
Protein kinase C delta type |
2 |
7 |
Small-scale |
0.768 | High |
|
|
GRB10
Growth factor receptor-bound protein 10 |
2 |
20 |
Small-scale |
0.768 | High |
|
|
JAK3
Tyrosine-protein kinase JAK3 |
2 |
20 |
Small-scale |
0.754 | High |
|
|
PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
9 |
8 |
Small-scale |
0.752 | High |
|
|
FBW1B
F-box/WD repeat-containing protein 11 |
2 |
10 |
Small-scale |
0.737 | High |
|
|
SH2B1
SH2B adapter protein 1 |
2 |
20 |
Small-scale |
0.727 | High |
|
|
PTN11
Tyrosine-protein phosphatase non-receptor type 11 |
6 |
10 |
Small-scale |
0.725 | High |
|
|
IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta |
1 |
8 |
Small-scale |
0.715 | High |
|
|
IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
1 |
9 |
Small-scale |
0.715 | High |
|
|
1433F
14-3-3 protein eta |
5 |
20 |
Small-scale |
0.714 | High |
|
|
P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma |
5 |
20 |
Small-scale |
0.714 | High |
|
|
FAK1
Focal adhesion kinase 1 |
1 |
20 |
Small-scale |
0.713 | High |
|
|
TRI72
Tripartite motif-containing protein 72 |
4 |
4 |
Small-scale |
0.708 | High |
|
|
1433B
14-3-3 protein beta/alpha |
5 |
20 |
Small-scale |
0.706 | High |
|
|
MTOR
Serine/threonine-protein kinase mTOR |
4 |
6 |
Small-scale |
0.702 | High |
|
|
1433G
14-3-3 protein gamma |
4 |
20 |
Small-scale |
0.694 | High |
|
|
1433E
14-3-3 protein epsilon |
4 |
9 |
Small-scale |
0.692 | High |
|
|
FBXW8
F-box/WD repeat-containing protein 8 |
3 |
13 |
Small-scale |
0.674 | High |
|
|
KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
3 |
5 |
Small-scale |
0.664 | High |
|
|
NCK2
Cytoplasmic protein NCK2 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
EGFR
Epidermal growth factor receptor |
1 |
20 |
High-throughput |
0.647 | High |
|
|
ERBB2
Receptor tyrosine-protein kinase erbB-2 |
1 |
20 |
High-throughput |
0.647 | High |
|
|
MK03
Mitogen-activated protein kinase 3 |
1 |
5 |
Small-scale |
0.647 | High |
|
|
IRS1
Insulin receptor substrate 1 |
1 |
13 |
Small-scale |
0.647 | High |
|
|
LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2 |
1 |
6 |
High-throughput |
0.647 | High |
|
|
PASK
PAS domain-containing serine/threonine-protein kinase |
1 |
7 |
Small-scale |
0.647 | High |
|
|
CYH3
Cytohesin-3 |
1 |
6 |
Small-scale |
0.646 | High |
|
|
CYH2
Cytohesin-2 |
1 |
6 |
Small-scale |
0.646 | High |
|
|
SOCS1
Suppressor of cytokine signaling 1 |
3 |
20 |
Small-scale |
0.640 | High |
|
|
BCAR3
Breast cancer anti-estrogen resistance protein 3 |
2 |
20 |
High-throughput |
0.634 | High |
|
|
1433T
14-3-3 protein theta |
3 |
20 |
Small-scale |
0.633 | High |
|
|
PTN1
Tyrosine-protein phosphatase non-receptor type 1 |
2 |
14 |
Small-scale |
0.619 | High |
|
|
DVL2
Segment polarity protein dishevelled homolog DVL-2 |
1 |
14 |
Small-scale |
0.618 | High |
|
|
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1 |
1 |
13 |
High-throughput |
0.618 | High |
|
|
FYN
Tyrosine-protein kinase Fyn |
1 |
20 |
Small-scale |
0.618 | High |
|
|
CSK22
Casein kinase II subunit alpha' |
1 |
13 |
Small-scale |
0.618 | High |
|
|
KC1A
Casein kinase I isoform alpha |
1 |
3 |
Small-scale |
0.618 | High |
|
|
GSK3B
Glycogen synthase kinase-3 beta |
1 |
10 |
Small-scale |
0.618 | High |
|
|
DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A |
1 |
12 |
High-throughput |
0.618 | High |
|
|
A16L1
Autophagy-related protein 16-1 |
1 |
10 |
High-throughput |
0.618 | High |
|
|
ALK
ALK tyrosine kinase receptor |
1 |
20 |
Small-scale |
0.618 | High |
|
|
FBW1A
F-box/WD repeat-containing protein 1A |
1 |
12 |
Small-scale |
0.618 | High |
|
|
NISCH
Nischarin |
1 |
9 |
Small-scale |
0.618 | High |
|
|
CD2AP
CD2-associated protein |
1 |
20 |
Small-scale |
0.618 | High |
|
|
1433S
14-3-3 protein sigma |
2 |
20 |
High-throughput |
0.601 | High |
|
|
SIR1
NAD-dependent protein deacetylase sirtuin-1 |
2 |
12 |
Small-scale |
0.601 | High |
|
|
NUMB
Protein numb homolog |
2 |
5 |
High-throughput |
0.594 | High |
|
|
P85B
Phosphatidylinositol 3-kinase regulatory subunit beta |
2 |
20 |
Small-scale |
0.584 | High |
|
|
UBF1
Nucleolar transcription factor 1 |
2 |
13 |
Small-scale |
0.584 | High |
|
|
CBL
E3 ubiquitin-protein ligase CBL |
2 |
11 |
Small-scale |
0.584 | High |
|
|
PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
2 |
8 |
Small-scale |
0.584 | High |
|
|
CBLB
E3 ubiquitin-protein ligase CBL-B |
2 |
10 |
Small-scale |
0.584 | High |
|
|
CUL7
Cullin-7 |
2 |
8 |
Small-scale |
0.584 | High |
|
|
PELI1
E3 ubiquitin-protein ligase pellino homolog 1 |
2 |
1 |
High-throughput |
0.576 | High |
|
|
DDR1
Epithelial discoidin domain-containing receptor 1 |
1 |
20 |
Small-scale |
0.575 | High |
|
|
HDAC2
Histone deacetylase 2 |
1 |
14 |
Small-scale |
0.573 | High |
|
|
RAD51
DNA repair protein RAD51 homolog 1 |
1 |
2 |
Small-scale |
0.561 | High |
|
|
TRAF4
TNF receptor-associated factor 4 |
1 |
7 |
Small-scale |
0.561 | High |
|
|
PELI2
E3 ubiquitin-protein ligase pellino homolog 2 |
1 |
1 |
Small-scale |
0.552 | High |
|
|
PTPRD
Receptor-type tyrosine-protein phosphatase delta |
1 |
6 |
Small-scale |
0.536 | High |
|
|
EGLN3
Prolyl hydroxylase EGLN3 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 |
1 |
4 |
Small-scale |
0.527 | High |
|
|
SMAD3
Mothers against decapentaplegic homolog 3 |
1 |
5 |
Small-scale |
0.515 | High |
|
|
KLHL9
Kelch-like protein 9 |
1 |
6 |
Small-scale |
0.515 | High |
|
|
KLH13
Kelch-like protein 13 |
1 |
6 |
Small-scale |
0.515 | High |
|
|
A4
Amyloid-beta precursor protein |
1 |
3 |
High-throughput |
0.501 | High |
|
|
UBC
Polyubiquitin-C [Cleaved into: Ubiquitin] |
1 |
5 |
Small-scale |
0.501 | High |
|
|
IL4RA
Interleukin-4 receptor subunit alpha |
1 |
9 |
Small-scale |
0.501 | High |
|
|
NEDD4
E3 ubiquitin-protein ligase NEDD4 |
1 |
11 |
High-throughput |
0.501 | High |
|
|
FBX25
F-box only protein 25 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
AP3S1
AP-3 complex subunit sigma-1 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
PTPRU
Receptor-type tyrosine-protein phosphatase U |
1 |
6 |
Small-scale |
0.501 | High |
|
|
PABP1
Polyadenylate-binding protein 1 |
1 |
9 |
Small-scale |
0.500 | High |
|
|
SOCS7
Suppressor of cytokine signaling 7 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
SOCS3
Suppressor of cytokine signaling 3 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
MTA2
Metastasis-associated protein MTA2 |
1 |
6 |
High-throughput |
0.479 | High |
|
|
ESR1
Estrogen receptor |
1 |
20 |
Small-scale |
0.479 | High |
|
|
BCL2
Apoptosis regulator Bcl-2 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
PTPRF
Receptor-type tyrosine-protein phosphatase F |
1 |
6 |
Small-scale |
0.479 | High |
|
|
1433Z
14-3-3 protein zeta/delta |
1 |
20 |
Small-scale |
0.479 | High |
|
|
CSK2B
Casein kinase II subunit beta |
1 |
3 |
Small-scale |
0.479 | High |
|
|
RNF4
E3 ubiquitin-protein ligase RNF4 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
TF65
Transcription factor p65 |
1 |
14 |
High-throughput |
0.479 | High |
|
|
B2CL1
Bcl-2-like protein 1 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
CUL1
Cullin-1 |
1 |
14 |
Small-scale |
0.479 | High |
|
|
CUL3
Cullin-3 |
1 |
14 |
Small-scale |
0.479 | High |
|
|
RN123
E3 ubiquitin-protein ligase RNF123 |
1 |
12 |
High-throughput |
0.479 | High |
|
|
ESR2
Estrogen receptor beta |
1 |
20 |
High-throughput |
0.479 | High |
|
|
USP9X
Ubiquitin carboxyl-terminal hydrolase 9X |
1 |
10 |
Small-scale |
0.479 | High |
|
|
ZDH18
Palmitoyltransferase ZDHHC18 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
ZRAN1
Ubiquitin thioesterase ZRANB1 |
1 |
6 |
High-throughput |
0.479 | High |
|
|
CD36
Platelet glycoprotein 4 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
IF4E
Eukaryotic translation initiation factor 4E |
1 |
1 |
Small-scale |
0.445 | High |
|
|
RFPLB
Ret finger protein-like 4B |
1 |
6 |
High-throughput |
0.445 | High |
|
|
CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2 |
1 |
7 |
High-throughput |
0.445 | High |
|
|
ZDH23
Palmitoyltransferase ZDHHC23 |
1 |
4 |
Small-scale |
0.437 | High |
|
|
FBX11
F-box only protein 11 |
1 |
0 |
High-throughput |
0.426 | High |
|
|
FBLN5
Fibulin-5 |
1 |
4 |
High-throughput |
0.407 | High |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
