Protein: SH3G3
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)

Gene: SH3G3, SH3GL3
Organism: Homo sapiens
Interactions: 146
UniProt ID: Q99963

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0007417 - central nervous system development
GO:0008289 - lipid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1307415

SH3G1
Endophilin-A2

7

17

Small-scale

0.971

High

1307430

SH3G2
Endophilin-A1

5

16

Small-scale

0.936

High

1307446

SH3G3
Endophilin-A3

3

16

Small-scale

0.871

High

338904

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.843

High

1173967

RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1

2

16

Small-scale

0.819

High

1305673

ATX2
Ataxin-2

3

20

Small-scale

0.688

High

791912

HD
Huntingtin

3

10

Small-scale

0.682

High

167009

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

2

2

High-throughput

0.659

High

872305

RD23B
UV excision repair protein RAD23 homolog B

2

13

High-throughput

0.659

High

1066046

ARHG6
Rho guanine nucleotide exchange factor 6

1

18

High-throughput

0.656

High

1266452

SHC3
SHC-transforming protein 3

1

20

High-throughput

0.656

High

1285181

SH3K1
SH3 domain-containing kinase-binding protein 1

2

20

Small-scale

0.649

High

228491

PRKN
E3 ubiquitin-protein ligase parkin

1

13

Small-scale

0.625

High

1307450

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

15

High-throughput

0.625

High

574425

RL35A
Large ribosomal subunit protein eL33

2

2

High-throughput

0.620

High

63093

NCF1B
Putative neutrophil cytosol factor 1B

1

20

High-throughput

0.618

High

537667

NCF1
Neutrophil cytosol factor 1

1

20

High-throughput

0.618

High

1307464

DYN3
Dynamin-3

1

20

Small-scale

0.618

High

952920

RHG08
Rho GTPase-activating protein 8

2

20

High-throughput

0.611

High

1045497

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.595

High

840808

DYN2
Dynamin-2

1

20

Small-scale

0.575

High

62540

RFOX3
RNA binding protein fox-1 homolog 3

2

5

High-throughput

0.571

High

152325

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

2

20

High-throughput

0.571

High

198970

RFOX2
RNA binding protein fox-1 homolog 2

2

9

High-throughput

0.571

High

1069643

STK38
Serine/threonine-protein kinase 38

2

9

High-throughput

0.571

High

335175

DHE3
Glutamate dehydrogenase 1, mitochondrial

2

2

High-throughput

0.571

High

388686

HSPB1
Heat shock protein beta-1

2

3

High-throughput

0.571

High

408668

KPCB
Protein kinase C beta type

2

6

High-throughput

0.571

High

416689

S10A6
Protein S100-A6

2

6

High-throughput

0.571

High

444929

ANXA5
Annexin A5

2

4

High-throughput

0.571

High

498334

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

2

High-throughput

0.571

High

509266

G6PD
Glucose-6-phosphate 1-dehydrogenase

2

1

High-throughput

0.571

High

531254

EF2
Elongation factor 2

2

3

High-throughput

0.571

High

551820

DESP
Desmoplakin

2

17

High-throughput

0.571

High

606478

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

2

1

High-throughput

0.571

High

607146

UBA1
Ubiquitin-like modifier-activating enzyme 1

2

1

High-throughput

0.571

High

639897

ITA3
Integrin alpha-3

2

2

High-throughput

0.571

High

643396

HMGB2
High mobility group protein B2

2

6

High-throughput

0.571

High

670801

BLVRB
Flavin reductase

2

1

High-throughput

0.571

High

850972

HDGF
Hepatoma-derived growth factor

2

1

High-throughput

0.571

High

892886

IF4A1
Eukaryotic initiation factor 4A-I

2

9

High-throughput

0.571

High

929351

IF5A1
Eukaryotic translation initiation factor 5A-1

2

2

High-throughput

0.571

High

930541

TYB10
Thymosin beta-10

2

1

High-throughput

0.571

High

973790

AKA12
A-kinase anchor protein 12

2

9

High-throughput

0.571

High

1046153

DX39B
Spliceosome RNA helicase DDX39B

2

7

High-throughput

0.571

High

1085340

FSCN1
Fascin

2

1

High-throughput

0.571

High

1267739

HS105
Heat shock protein 105 kDa

2

9

High-throughput

0.571

High

1294846

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

11

High-throughput

0.571

High

1307456

RFOX1
RNA binding protein fox-1 homolog 1

2

7

High-throughput

0.571

High

1281828

FBX32
F-box only protein 32

1

2

Small-scale

0.561

High

671587

KCY
UMP-CMP kinase

2

0

High-throughput

0.547

High

893463

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

0

High-throughput

0.547

High

922895

RL32
Large ribosomal subunit protein eL32

2

0

High-throughput

0.547

High

1067881

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

2

0

High-throughput

0.547

High

1304228

PARK7
Parkinson disease protein 7

2

0

High-throughput

0.547

High

277391

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

1

High-throughput

0.541

High

838419

CRIP1
Cysteine-rich protein 1

1

12

High-throughput

0.541

High

839083

EMD
Emerin

1

1

High-throughput

0.541

High

869726

TERF1
Telomeric repeat-binding factor 1

1

5

High-throughput

0.541

High

928005

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

20

High-throughput

0.541

High

1292524

TOE1
Target of EGR1 protein 1

1

2

High-throughput

0.541

High

1307458

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

9

High-throughput

0.541

High

586942

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.536

High

412329

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.528

High

246609

MCE1
mRNA-capping enzyme

2

2

High-throughput

0.521

High

449802

HMGB1
High mobility group protein B1

2

6

High-throughput

0.521

High

455804

PARP1
Poly [ADP-ribose] polymerase 1

2

4

High-throughput

0.521

High

643903

SYVC
Valine--tRNA ligase

2

1

High-throughput

0.521

High

737455

LONM
Lon protease homolog, mitochondrial

2

3

High-throughput

0.521

High

827545

EFTU
Elongation factor Tu, mitochondrial

2

3

High-throughput

0.521

High

828163

DHE4
Glutamate dehydrogenase 2, mitochondrial

2

2

High-throughput

0.521

High

901418

CH10
10 kDa heat shock protein, mitochondrial

2

1

High-throughput

0.521

High

949715

RL36A
Large ribosomal subunit protein eL42

2

2

High-throughput

0.521

High

1022586

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

2

5

High-throughput

0.521

High

1024083

ACACA
Acetyl-CoA carboxylase 1

2

1

High-throughput

0.521

High

1051909

IF4A2
Eukaryotic initiation factor 4A-II

2

6

High-throughput

0.521

High

1126034

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

2

20

High-throughput

0.521

High

1153637

IF5AL
Eukaryotic translation initiation factor 5A-1-like

2

2

High-throughput

0.521

High

1159522

SCYL2
SCY1-like protein 2

2

7

High-throughput

0.521

High

1281913

RL36L
Ribosomal protein eL42-like

2

2

High-throughput

0.521

High

1307448

SPNDC
Spindlin interactor and repressor of chromatin-binding protein

2

1

High-throughput

0.521

High

1307463

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

2

6

High-throughput

0.521

High

1307465

RCL1
RNA 3'-terminal phosphate cyclase-like protein

2

1

High-throughput

0.521

High

1307466

TR150
Thyroid hormone receptor-associated protein 3

2

8

High-throughput

0.521

High

329124

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

443759

VIME
Vimentin

1

20

High-throughput

0.508

High

1087976

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

8

High-throughput

0.508

High

1267800

SEPT8
Septin-8

1

3

High-throughput

0.508

High

1307462

CBLC
E3 ubiquitin-protein ligase CBL-C

1

20

High-throughput

0.508

High

815709

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

4

Small-scale

0.501

High

1130501

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

Small-scale

0.501

High

1307454

DNJC5
DnaJ homolog subfamily C member 5

1

9

High-throughput

0.501

High

147354

DPYL4
Dihydropyrimidinase-related protein 4

1

3

High-throughput

0.494

High

854823

GDIR1
Rho GDP-dissociation inhibitor 1

1

1

High-throughput

0.494

High

993572

TLE5
TLE family member 5

1

1

High-throughput

0.494

High

1183763

DPPA4
Developmental pluripotency-associated protein 4

1

4

High-throughput

0.494

High

1216969

EGFL6
Epidermal growth factor-like protein 6

1

4

High-throughput

0.494

High

1274002

IGSF2
Immunoglobulin superfamily member 2

1

8

High-throughput

0.494

High

1307452

WDR33
pre-mRNA 3' end processing protein WDR33

1

2

High-throughput

0.494

High

81935

B7ZMA4
LOC553158 protein

1

20

High-throughput

0.479

High

436949

ACM4
Muscarinic acetylcholine receptor M4

1

20

Small-scale

0.479

High

445811

ADA2A
Alpha-2A adrenergic receptor

1

20

Small-scale

0.479

High

610496

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

1217585

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

20

High-throughput

0.479

High

962315

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

4

High-throughput

0.470

High

1231851

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.460

High

69705

B1AHC3
PRR5-ARHGAP8 readthrough

1

20

High-throughput

0.445

High

49364

T120B
Transmembrane protein 120B

1

1

High-throughput

0.439

High

282722

RNF8
E3 ubiquitin-protein ligase RNF8

1

8

High-throughput

0.439

High

1307461

PRAF1
Prenylated Rab acceptor protein 1

1

2

High-throughput

0.439

High

1307469

GOT1B
Vesicle transport protein GOT1B

1

1

High-throughput

0.439

High

534051

ADRB3
Beta-3 adrenergic receptor

1

7

Small-scale

0.437

High

723003

HRH1
Histamine H1 receptor

1

20

Small-scale

0.437

High

723749

DRD3
D(3) dopamine receptor

1

20

Small-scale

0.437

High

1148191

RNF43
E3 ubiquitin-protein ligase RNF43

1

19

High-throughput

0.437

High

1152066

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.437

High

1286676

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.437

High

724130

K1C9
Keratin, type I cytoskeletal 9

1

20

High-throughput

0.417

High

1307468

SNX24
Sorting nexin-24

1

8

High-throughput

0.417

High

70549

HGB1A
Putative high mobility group protein B1-like 1

1

6

High-throughput

0.407

High

211237

BUB3
Mitotic checkpoint protein BUB3

2

0

High-throughput

0.298

High

438980

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

2

0

High-throughput

0.298

High

604190

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

2

0

High-throughput

0.298

High

678663

METK2
S-adenosylmethionine synthase isoform type-2

2

0

High-throughput

0.298

High

682524

PUR9
Bifunctional purine biosynthesis protein ATIC

2

0

High-throughput

0.298

High

847629

BAP31
B-cell receptor-associated protein 31

2

0

High-throughput

0.298

High

958512

CYC
Cytochrome c

2

0

High-throughput

0.298

High

1024992

MTAP
S-methyl-5'-thioadenosine phosphorylase

2

0

High-throughput

0.298

High

1058146

BMS1
Ribosome biogenesis protein BMS1 homolog

2

0

High-throughput

0.298

High

1086385

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

2

0

High-throughput

0.298

High

1243741

PPHLN
Periphilin-1

2

0

High-throughput

0.298

High

1283362

RM24
Large ribosomal subunit protein uL24m

2

0

High-throughput

0.298

High

1307451

RM32
Large ribosomal subunit protein bL32m

2

0

High-throughput

0.298

High

1307455

RT18A
Large ribosomal subunit protein mL66

2

0

High-throughput

0.298

High

1307457

MAT2B
Methionine adenosyltransferase 2 subunit beta

2

0

High-throughput

0.298

High

1307459

SUN2
SUN domain-containing protein 2

2

0

High-throughput

0.298

High

1307460

DPP2
Dipeptidyl peptidase 2

2

0

High-throughput

0.298

High

1307467

MEMO1
Protein MEMO1

2

0

High-throughput

0.298

High

173512

RER1
Protein RER1

1

0

High-throughput

0.282

High

1120676

CD017
Uncharacterized protein C4orf17

1

0

High-throughput

0.282

High

1307447

ANKMT
Adenine nucleotide translocase lysine N-methyltransferase

1

0

High-throughput

0.282

High

1307449

TGT
Queuine tRNA-ribosyltransferase catalytic subunit 1

1

0

High-throughput

0.282

High

1307453

CK068
UPF0696 protein C11orf68

1

0

High-throughput

0.282

High

1307470

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.282

High

533623

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024