HitPredict

Interactor 1: UBS3B (Q8TF42)
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)
Gene: UBASH3B

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36179048
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 649 Hs			1 419
+	Hs
		772923 UBS3B_HUMAN (1-649): 0: 1066: 100.00		MYH9_HUMAN (11-402): 4.52e-11: 67.3: 9.93
+	Hs
		773233 UBS3B_HUMAN (1-649): 0: 1066: 100.00		MYH10_HUMAN (27-387): 1.17e-10: 65.8: 14.09
+	Hs
		943835 UBS3A_HUMAN (12-643): 0: 947: 43.37		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		1154148 SH3K1_HUMAN (221-375): 5.04e-29: 124: 25.00		ITSN1_HUMAN (24-403): 1.07e-30: 127: 12.15
+	Hs
		1046402 UBXN1_HUMAN (35-97): 3.56e-22: 99.1: 47.69		OPTN_HUMAN (67-418): 2.8e-38: 147: 27.25
+	Hs
		772723 GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56		MYH9_HUMAN (11-402): 4.52e-11: 67.3: 9.93
+	Hs
		773152 GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56		MYH10_HUMAN (27-387): 1.17e-10: 65.8: 14.09
+	Hs
		776799 GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56		MYH11_HUMAN (13-392): 2.71e-09: 61.5: 13.42
+	Hs
		987809 GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56		MY18A_HUMAN (10-390): 4.25e-09: 60.8: 15.89
+	Hs
		1133142 LASP1_HUMAN (254-315): 1.29e-12: 70.2: 30.65		OPTN_HUMAN (67-418): 2.8e-38: 147: 27.25
+	Hs
		635548 NEBU_HUMAN (256-315): 6.9e-11: 67.9: 33.33		OPTN_HUMAN (67-418): 2.8e-38: 147: 27.25
+	Hs
		320218 SRBS2_HUMAN (230-317): 1.4e-22: 105: 27.84		MYH9_HUMAN (11-402): 4.52e-11: 67.3: 9.93
+	Hs
		320256 SRBS2_HUMAN (230-317): 1.4e-22: 105: 27.84		MY18A_HUMAN (10-390): 4.25e-09: 60.8: 15.89