HitPredict

Interactor 1: MB3L1 (Q8WWY6)
Methyl-CpG-binding domain protein 3-like 1 (MBD3-like protein 1)
Gene: MBD3L1

Interactor 2: MTA3 (Q9BTC8)
Metastasis-associated protein MTA3
Gene: MTA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 194 Hs			1 594
+	Hs
		352235 MBD3_HUMAN (1-193): 3.42e-102: 297: 44.56		MTA3_HUMAN (1-594): 0: 724: 100.00
+	Hs
		1413355 MBD2_HUMAN (1-182): 5.64e-85: 258: 41.76		MTA3_HUMAN (1-594): 0: 724: 100.00
+	Hs
		352130 MBD3_HUMAN (1-193): 3.42e-102: 297: 44.56		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Mm
		1317411 MBD3_MOUSE (1-193): 1.27e-101: 296: 43.52		MTA1_MOUSE (1-586): 0: 625: 68.81
+	Hs
		1340904 MB3L2_HUMAN (26-187): 5.84e-61: 190: 45.73		MTA3_HUMAN (1-594): 0: 724: 100.00
+	Hs
		1102611 MB3L1_HUMAN (1-194): 1.27e-98: 285: 100.00		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Mm
		1455958 MBD3_MOUSE (1-193): 1.27e-101: 296: 43.52		MTA2_MOUSE (1-584): 0: 613: 64.57
+	Hs
		316714 MBD3_HUMAN (1-193): 3.42e-102: 297: 44.56		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		316931 MB3L1_HUMAN (1-194): 1.27e-98: 285: 100.00		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		1102676 MBD2_HUMAN (1-182): 5.64e-85: 258: 41.76		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Mm
		1455959 MBD2_MOUSE (1-182): 1.15e-84: 257: 41.76		MTA2_MOUSE (1-584): 0: 613: 64.57
+	Hs
		317018 MBD2_HUMAN (1-182): 5.64e-85: 258: 41.76		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		1102606 MB3L2_HUMAN (26-187): 5.84e-61: 190: 45.73		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		316924 MB3L2_HUMAN (26-187): 5.84e-61: 190: 45.73		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Dm
		84939 Q9VHB7_DROME (19-172): 3.69e-59: 190: 28.66		B7Z0T5_DROME (10-586): 1.03e-169: 506: 43.28
+	Dm
		2602 A0A0B4KGZ0_DROME (19-172): 4.22e-59: 190: 28.66		Q9VNF6_DROME (1-70): 5.2e-24: 109: 68.57