HitPredict

Interactor 1: SREK1 (Q8WXA9)
Splicing regulatory glutamine/lysine-rich protein 1 (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) (Splicing regulatory protein 508) (SRrp508)
Gene: SREK1

Interactor 2: SRSF8 (Q9BRL6)
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)
Gene: SRSF8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.897

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 14559993
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
GO:0008380 - RNA splicing
GO:0016607 - nuclear speck
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 508
Hs

1 282
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ Sp
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025