Interactor 1: PLK4 (O00444)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)
Gene: PLK4
Interactor 2: CE152 (O94986)
Centrosomal protein of 152 kDa (Cep152)
Gene: CEP152
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26638075, 24613305, 26496610, 27872092, 24997597, 20852615, 21059844, 26188084 |
| Identification Methods | proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, fluorescence polarization spectroscopy, x-ray crystallography, molecular sieving |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0007099 - centriole replication GO:0098535 - de novo centriole assembly involved in multi-ciliated epithelial cell differentiation and 3 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
