HitPredict

Interactor 1: PRP6 (Q91YR7)
Pre-mRNA-processing factor 6 (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: Prpf6

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_19~WD40
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 941 Mm			1 441
+	Hs
		285013 PRP6_HUMAN (1-941): 0: 650: 98.30		EED_HUMAN (1-441): 1.63e-90: 283: 100.00
+	Hs
		321618 PRP6_HUMAN (1-941): 0: 650: 98.30		FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32
+	Hs
		321626 PRP6_HUMAN (1-941): 0: 650: 98.30		SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29
+	Hs
		321479 PRP6_HUMAN (1-941): 0: 650: 98.30		WDR5_HUMAN (335-440): 3.34e-14: 75.4: 15.09
+	Hs
		209174 PRP6_HUMAN (1-941): 0: 650: 98.30		PRP4_HUMAN (332-437): 4.05e-09: 60.4: 15.79
+	Hs
		285459 CRNL1_HUMAN (520-938): 2.73e-34: 143: 16.12		EED_HUMAN (1-441): 1.63e-90: 283: 100.00
+	Mm
		991141 CRNL1_MOUSE (520-938): 1.46e-30: 131: 16.53		EED_MOUSE (1-441): 1.63e-90: 283: 100.00
+	Hs
		285281 RRP5_HUMAN (439-693): 8.32e-26: 117: 13.23		EED_HUMAN (1-441): 1.63e-90: 283: 100.00
+	Mm
		1237812 RRP5_MOUSE (500-780): 3.9e-22: 105: 15.07		EED_MOUSE (1-441): 1.63e-90: 283: 100.00
+	Ca
		515424 Q5ADP3_CANAL (246-589): 2.14e-35: 147: 11.31		TUP1_CANAL (4-263): 3e-56: 195: 14.50
+	Dm
		609146 CRN_DROME (417-940): 4.16e-38: 154: 18.28		Q9VPL0_DROME (221-441): 1.35e-28: 117: 13.90
+	Dm
		1264419 Q7K0X3_DROME (247-888): 2.07e-46: 183: 12.37		Q9XZ19_DROME (96-279): 7.88e-17: 83.2: 23.24
+	Hs
		1387547 CRNL1_HUMAN (520-938): 2.73e-34: 143: 16.12		SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29
+	Hs
		1130862 RRP5_HUMAN (439-693): 8.32e-26: 117: 13.23		NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45
+	Hs
		1130811 RRP5_HUMAN (439-693): 8.32e-26: 117: 13.23		SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29
+	Hs
		1288037 PRP39_HUMAN (380-858): 2.54e-18: 92.2: 14.90		FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32
+	Hs
		964951 RRP5_HUMAN (439-693): 8.32e-26: 117: 13.23		WDR5_HUMAN (335-440): 3.34e-14: 75.4: 15.09
+	Hs
		1288055 PRP39_HUMAN (380-858): 2.54e-18: 92.2: 14.90		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Sp
		238287 CYC8_SCHPO (275-402): 1.99e-13: 76.8: 15.79		TUP11_SCHPO (360-440): 8.75e-14: 75.4: 18.52
+	Sp
		238288 CYC8_SCHPO (275-402): 1.99e-13: 76.8: 15.79		TUP12_SCHPO (332-439): 3.02e-13: 73.5: 14.82