HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_19~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 941
+	Mm
		1362416 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		PRP6_MOUSE (1-941): 0: 623: 98.30
+	Hs
		321618 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		PRP6_HUMAN (1-941): 0: 621: 100.00
+	Hs
		321626 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		PRP6_HUMAN (1-941): 0: 621: 100.00
+	Mm
		1298591 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		OGT1_MOUSE (214-711): 2.63e-64: 237: 12.64
+	Mm
		991141 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		CRNL1_MOUSE (543-939): 3.77e-42: 167: 16.82
+	Hs
		285459 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		CRNL1_HUMAN (521-932): 8.48e-41: 164: 12.50
+	Hs
		185995 TBL1R_HUMAN (25-267): 1.29e-47: 172: 14.40		OGT1_HUMAN (214-711): 1.18e-64: 238: 12.64
+	Hs
		285281 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		RRP5_HUMAN (474-761): 8.36e-27: 120: 14.09
+	Mm
		1237812 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		RRP5_MOUSE (504-761): 3.01e-23: 109: 14.55
+	Mm
		1362730 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		SYF1_MOUSE (109-527): 3.36e-12: 72.6: 12.61
+	Sp
		238287 TUP11_SCHPO (360-440): 8.75e-14: 75.4: 18.52		CYC8_SCHPO (181-692): 2.81e-50: 195: 11.51
+	Ca
		515424 TUP1_CANAL (4-263): 3e-56: 195: 14.50		Q5ADP3_CANAL (265-388): 1.13e-10: 68: 13.95
+	Hs
		1387547 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		CRNL1_HUMAN (521-932): 8.48e-41: 164: 12.50
+	Dm
		609146 Q9VPL0_DROME (221-441): 1.35e-28: 117: 13.90		CRN_DROME (247-671): 1.5e-26: 118: 15.37
+	Dm
		1264419 Q9XZ19_DROME (96-279): 7.88e-17: 83.2: 23.24		Q7K0X3_DROME (381-940): 3.31e-35: 147: 11.24
+	Hs
		1130862 NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45		RRP5_HUMAN (474-761): 8.36e-27: 120: 14.09
+	Hs
		1288037 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		PRP39_HUMAN (425-927): 1.16e-23: 109: 15.92
+	Hs
		1130811 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		RRP5_HUMAN (474-761): 8.36e-27: 120: 14.09
+	Dm
		55550 Q9VPL0_DROME (221-441): 1.35e-28: 117: 13.90		SYF1_DROME (229-666): 3.2e-20: 98.8: 13.12
+	Hs
		1387577 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		SYF1_HUMAN (109-527): 3.36e-12: 72.6: 13.05