HitPredict

Interactor 1: REV1 (Q920Q2)
DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase)
Gene: REV1

Interactor 2: POLH (Q9JJN0)
DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog)
Gene: POLH

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 14657033, 22244149, 18242152
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IMS~IMS, IMS~IMS_C, IMS~POLH-Rev1_HhH, IMS_C~IMS_C, IMS~IMS_HHH_1, IMS_C~IMS_HHH_1
Common GO terms GO:0003684 - damaged DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1249
Mm

1 694
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp
+ Dm
+ Sp
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025