Protein: POLH
DNA polymerase eta (EC 2.7.7.7) (Radiation-sensitive protein 30)

Gene: POLH, RAD30
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: Q04049

Gene Ontology (top 5):
GO:0003684 - damaged DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005657 - replication fork
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

586485

PCNA
Proliferating cell nuclear antigen

17

14

Small-scale

0.986

High

554765

REV1
DNA repair protein REV1

6

13

Small-scale

0.944

High

509705

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

9

Small-scale

0.642

High

805632

LSM12
Protein LSM12

2

0

Small-scale

0.605

High

819704

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

917893

MRH4
ATP-dependent RNA helicase MRH4, mitochondrial

1

0

High-throughput

0.518

High

1044960

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

High-throughput

0.518

High

850523

ECO1
N-acetyltransferase ECO1

1

2

Small-scale

0.501

High

367114

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.500

High

425145

OTC
Ornithine carbamoyltransferase

1

1

High-throughput

0.500

High

452966

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.500

High

676313

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.500

High

871445

HLJ1
Protein HLJ1

1

2

High-throughput

0.494

High

448796

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.493

High

557034

AAKG
5'-AMP-activated protein kinase subunit gamma

1

0

High-throughput

0.493

High

816547

SNU13
13 kDa ribonucleoprotein-associated protein

1

0

High-throughput

0.493

High

1044959

GAL83
SNF1 protein kinase subunit beta-3

1

0

High-throughput

0.493

High

533483

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

4

Small-scale

0.481

High

746100

RAD5
DNA repair protein RAD5

1

2

Small-scale

0.481

High

364726

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

453776

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.479

High

484792

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.479

High

607786

HXKG
Glucokinase-1

1

0

High-throughput

0.479

High

645525

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.479

High

571300

DPOZ
DNA polymerase zeta catalytic subunit

1

5

Small-scale

0.479

High

680614

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

1

High-throughput

0.479

High

807715

REV7
DNA polymerase zeta processivity subunit

1

1

Small-scale

0.479

High

863240

DPOD2
DNA polymerase delta small subunit

1

2

Small-scale

0.479

High

865444

DPOD3
DNA polymerase delta subunit 3

1

1

Small-scale

0.479

High

481754

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

525042

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

546149

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

752689

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

1035069

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

438547

UBC2
Ubiquitin-conjugating enzyme E2 2

1

2

Small-scale

0.408

High

808339

TVP23
Golgi apparatus membrane protein TVP23

1

0

High-throughput

0.282

High

446245

PHSG
Glycogen phosphorylase

1

0

High-throughput

0.269

Low

836880

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.261

Low

1044961

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

816742

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

863721

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025