HitPredict

Interactor 1: TOPB1 (Q92547)
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Gene: TOPBP1

Interactor 2: MCCA (Q96RQ3)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)
Gene: MCCC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33503405
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1522 Hs			1 725
+	Hs
		425832 TOPB1_HUMAN (1-1522): 0: 1823: 100.00		PCCA_HUMAN (1-715): 0: 649: 37.38
+	Hs
		1094224 TOPB1_HUMAN (1-1522): 0: 1823: 100.00		ACACA_HUMAN (29-725): 0: 609: 25.40
+	Hs
		547181 TOPB1_HUMAN (1-1522): 0: 1823: 100.00		PYC_HUMAN (47-707): 0: 601: 33.04
+	Hs
		144306 TOPB1_HUMAN (1-1522): 0: 1823: 100.00		ACACB_HUMAN (24-723): 0: 578: 26.01
+	Hs
		697604 TOPB1_HUMAN (1-1522): 0: 1823: 100.00		PYR1_HUMAN (6-467): 1.37e-72: 259: 15.76