HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21182203
Identification Methods	cosedimentation through density gradient
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 759
+	Hs
		397154 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1273852 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		MICA3_HUMAN (271-544): 5.73e-43: 170: 23.93
+	Hs
		637150 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		CSRP1_HUMAN (254-449): 3.71e-34: 131: 15.82
+	Hs
		159246 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		396474 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		MILK2_HUMAN (295-569): 1.43e-37: 153: 22.95
+	Hs
		395489 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		CSRP1_HUMAN (254-449): 3.71e-34: 131: 15.82
+	Hs
		878525 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		PAXI_HUMAN (268-446): 6.47e-14: 77.3: 14.53
+	Hs
		159129 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		395682 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		PAXI_HUMAN (268-446): 6.47e-14: 77.3: 14.53
+	Hs
		404086 GCR_HUMAN (3-495): 1.13e-103: 330: 22.64		CSRP2_HUMAN (254-450): 3.37e-41: 151: 18.27
+	Rn
		443606 GCR_RAT (3-495): 5.91e-100: 321: 23.03		LASP1_RAT (389-572): 1.31e-40: 151: 18.78
+	Hs
		212701 GCR_HUMAN (3-495): 1.13e-103: 330: 22.64		TGFI1_HUMAN (263-447): 1.58e-16: 85: 15.64
+	Hs
		212704 ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59		TGFI1_HUMAN (263-447): 1.58e-16: 85: 15.64