HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: CSRP1 (P21291)
Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141)
Gene: CSRP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	25640309
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 193
+	Hs
		397017 ESR1_HUMAN (1-595): 0: 599: 100.00		PDLI7_HUMAN (68-190): 2.73e-25: 103: 16.54
+	Hs
		395682 ESR1_HUMAN (1-595): 0: 599: 100.00		PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05
+	Hs
		397154 ESR1_HUMAN (1-595): 0: 599: 100.00		LIMA1_HUMAN (3-117): 9.1e-21: 91: 27.83
+	Hs
		159129 ESR1_HUMAN (1-595): 0: 599: 100.00		ABLM1_HUMAN (74-192): 3.01e-14: 72: 18.49
+	Hs
		637150 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		CSRP1_HUMAN (1-178): 3.16e-42: 142: 100.00
+	Hs
		1367365 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		PDLI7_HUMAN (68-190): 2.73e-25: 103: 16.54
+	Hs
		1367014 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		PDLI5_HUMAN (7-126): 7.38e-24: 99.7: 17.50
+	Hs
		878525 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05
+	Hs
		1367514 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		LIMA1_HUMAN (3-117): 9.1e-21: 91: 27.83
+	Hs
		404086 GCR_HUMAN (5-557): 4.69e-109: 346: 22.51		CSRP2_HUMAN (1-193): 2.08e-45: 150: 79.28
+	Hs
		1273852 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		MICA3_HUMAN (3-118): 4.45e-18: 83.3: 27.94
+	Hs
		1366955 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		LPP_HUMAN (69-186): 2.91e-17: 80.9: 16.79
+	Hs
		159246 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		ABLM1_HUMAN (74-192): 3.01e-14: 72: 18.49
+	Hs
		253931 GCR_HUMAN (5-557): 4.69e-109: 346: 22.51		LPXN_HUMAN (4-128): 8.17e-21: 90.1: 15.20
+	Hs
		212701 GCR_HUMAN (5-557): 4.69e-109: 346: 22.51		TGFI1_HUMAN (6-67): 3.58e-10: 60.1: 27.42
+	Hs
		212704 ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16		TGFI1_HUMAN (6-67): 3.58e-10: 60.1: 27.42