HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: PAR3L (Q8TEW8)
Partitioning defective 3 homolog B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein) (PAR3-beta) (Partitioning defective 3-like protein) (PAR3-L protein)
Gene: PARD3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	30217970
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 926 Hs			1 1205
+	Hs
		159249 CSKP_HUMAN (1-926): 0: 973: 100.00		DLG3_HUMAN (25-525): 3.4e-49: 191: 14.95
+	Hs
		159190 CSKP_HUMAN (1-926): 0: 973: 100.00		DLG4_HUMAN (334-877): 1.37e-48: 187: 16.58
+	Mm
		251104 CSKP_MOUSE (1-926): 0: 973: 99.89		DLG1_MOUSE (13-699): 2.65e-45: 179: 12.40
+	Hs
		159200 CSKP_HUMAN (1-926): 0: 973: 100.00		DLG1_HUMAN (47-699): 1.29e-44: 177: 11.61
+	Rn
		1144009 CSKP_RAT (1-926): 0: 945: 97.73		DLG1_RAT (15-585): 2.59e-44: 176: 13.49
+	Hs
		1021538 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		PARD3_HUMAN (1-1181): 5.16e-119: 403: 34.95
+	Hs
		1021501 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		DLG2_HUMAN (305-997): 4.82e-56: 212: 16.23
+	Mm
		1143555 MPP2_MOUSE (347-926): 5.87e-155: 469: 37.48		DLG4_MOUSE (334-877): 1.2e-48: 187: 16.58
+	Hs
		1021542 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		DLG3_HUMAN (25-525): 3.4e-49: 191: 14.95
+	Mm
		1113136 Q3UP61_MOUSE (405-923): 2.92e-146: 457: 22.06		DLG4_MOUSE (334-877): 1.2e-48: 187: 16.58
+	Hs
		1021489 MPP2_HUMAN (420-926): 8.18e-154: 466: 39.27		DLG1_HUMAN (47-699): 1.29e-44: 177: 11.61
+	Mm
		1143387 DLG1_MOUSE (405-923): 1.81e-145: 456: 22.06		DLG4_MOUSE (334-877): 1.2e-48: 187: 16.58
+	Hs
		1021482 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		DLG1_HUMAN (47-699): 1.29e-44: 177: 11.61
+	Rn
		1144014 DLG2_RAT (352-923): 1.29e-144: 452: 21.56		DLG1_RAT (15-585): 2.59e-44: 176: 13.49
+	Dm
		116475 M9PJD0_DROME (287-926): 2.45e-154: 500: 24.89		PATJ_DROME (470-599): 8.5e-13: 75: 21.54
+	Dm
		116472 M9PJD0_DROME (287-926): 2.45e-154: 500: 24.89		Q0KHR3_DROME (734-884): 3.06e-10: 67.2: 29.80
+	Dm
		677695 DLG1_DROME (445-923): 5.3e-145: 456: 21.50		SCRIB_DROME (504-689): 1.03e-13: 78.5: 18.52
+	Hs
		1232484 PALS1_HUMAN (361-925): 9.64e-148: 454: 27.84		INADL_HUMAN (162-321): 1.92e-13: 77.8: 14.91
+	Hs
		280053 PALS1_HUMAN (361-925): 9.64e-148: 454: 27.84		MPDZ_HUMAN (499-735): 8.56e-13: 75.4: 18.83
+	Hs
		1232496 PALS1_HUMAN (361-925): 9.64e-148: 454: 27.84		MAGI1_HUMAN (333-687): 4.75e-12: 73.1: 13.58