HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21951318
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 1294
+	Hs
		397210 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		MYO6_HUMAN (1-1294): 0: 1078: 100.00
+	Hs
		404541 GCR_HUMAN (3-495): 1.13e-103: 330: 22.64		MYO6_HUMAN (1-1294): 0: 1078: 100.00
+	Hs
		404030 GCR_HUMAN (3-495): 1.13e-103: 330: 22.64		MYO7A_HUMAN (1-964): 0: 934: 29.49
+	Hs
		520451 ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59		MYO6_HUMAN (1-1294): 0: 1078: 100.00
+	Hs
		556943 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		MYH7_HUMAN (740-1206): 6.26e-16: 85.9: 14.08
+	Hs
		1367679 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		MYO5A_HUMAN (712-1138): 6.86e-16: 85.8: 9.11
+	Hs
		1367573 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		MYO5B_HUMAN (722-1180): 1.82e-12: 74.6: 10.39
+	Hs
		67566 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		MYH7B_HUMAN (761-1095): 2.03e-11: 71.2: 14.33
+	Hs
		772936 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70
+	Hs
		397312 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		MYO5A_HUMAN (712-1138): 6.86e-16: 85.8: 9.11
+	Hs
		395408 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		MYH6_HUMAN (760-1113): 5.52e-10: 66.2: 18.89
+	Hs
		395602 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70
+	Hs
		625771 RXRA_HUMAN (13-502): 1.61e-119: 361: 25.71		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70
+	Hs
		520482 ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59		MYO5A_HUMAN (712-1138): 6.86e-16: 85.8: 9.11
+	Hs
		520447 ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59		MYO5B_HUMAN (722-1180): 1.82e-12: 74.6: 10.39
+	Hs
		520397 ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59		MYO5C_HUMAN (1079-1293): 3.34e-12: 73.8: 10.81
+	Hs
		519794 ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59		MYH10_HUMAN (762-1135): 7.13e-10: 65.8: 15.54