Interactor 1: B2CL2 (Q92843)
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)
Gene: BCL2L2
Interactor 2: BBC3 (Q9BXH1)
Bcl-2-binding component 3, isoforms 1/2 (JFY-1) (p53 up-regulated modulator of apoptosis)
Gene: BBC3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.76 | 1.00 | 0.873 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, unassigned3799, 16697956, 15694340 |
| Identification Methods | anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, surface plasmon resonance |
| Interaction Type | association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~PUMA |
| Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
