HitPredict

Interactor 1: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (Protein lactyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~MOZ_SAS
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035092 - sperm DNA condensation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 127
+	Mm
		1225799 KAT5_MOUSE (1-513): 0: 852: 99.81		H2B2B_MOUSE (5-127): 1.83e-54: 168: 85.37
+	Hs
		754931 KAT5_HUMAN (1-513): 0: 852: 100.00		H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83
+	Hs
		980983 KAT5_HUMAN (1-513): 0: 852: 100.00		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		1323946 KAT5_HUMAN (1-513): 0: 852: 100.00		H2B3B_HUMAN (1-127): 9.02e-51: 158: 85.83
+	Dm
		380887 TIP60_DROME (7-512): 0: 709: 57.60		H2B_DROME (37-127): 3.49e-47: 149: 94.51
+	Hs
		1163209 KAT8_HUMAN (162-504): 3.52e-168: 485: 46.67		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		981101 KAT8_HUMAN (162-504): 3.52e-168: 485: 46.67		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		331962 KAT7_HUMAN (111-504): 1.87e-157: 463: 40.30		H2B1O_HUMAN (5-127): 3.42e-54: 167: 86.18
+	Hs
		332009 KAT7_HUMAN (111-504): 1.87e-157: 463: 40.30		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		331987 KAT7_HUMAN (111-504): 1.87e-157: 463: 40.30		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		1208863 KAT6A_HUMAN (70-504): 1.51e-138: 442: 37.23		H2B2F_HUMAN (5-127): 1.83e-54: 168: 85.37
+	Hs
		1163108 KAT6A_HUMAN (70-504): 1.51e-138: 442: 37.23		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		659926 KAT6A_HUMAN (70-504): 1.51e-138: 442: 37.23		H2B1O_HUMAN (5-127): 3.42e-54: 167: 86.18
+	Hs
		1163094 KAT6B_HUMAN (144-504): 8.8e-137: 438: 40.65		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		659922 KAT6B_HUMAN (144-504): 8.8e-137: 438: 40.65		H2B1O_HUMAN (5-127): 3.42e-54: 167: 86.18
+	Hs
		1361556 KAT6B_HUMAN (144-504): 8.8e-137: 438: 40.65		H2B1H_HUMAN (5-127): 5.54e-54: 166: 85.37
+	Sc
		381478 SAS3_YEAST (208-504): 1.24e-123: 382: 40.66		H2B2_YEAST (4-126): 4.48e-41: 134: 69.36
+	Sc
		381660 ESA1_YEAST (21-103): 6.03e-11: 66.3: 38.10		H2B2_YEAST (4-126): 4.48e-41: 134: 69.36