HitPredict

Interactor 1: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Interactor 2: EAF3 (Q9Y0I1)
NuA4 complex subunit EAF3 homolog (Protein MRG15)
Gene: MRG15

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19114561
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0031507 - heterochromatin formation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 521 Dm			1 424
+	Hs
		1368175 HDAC2_HUMAN (2-488): 0: 659: 76.59		MO4L1_HUMAN (13-423): 7.01e-102: 309: 34.67
+	Mm
		148669 HDAC1_MOUSE (3-443): 0: 640: 81.18		MO4L1_MOUSE (13-423): 9e-102: 308: 34.67
+	Hs
		1110146 HDAC1_HUMAN (3-443): 0: 637: 81.18		MO4L1_HUMAN (13-423): 7.01e-102: 309: 34.67
+	Hs
		1136827 HDAC2_HUMAN (2-488): 0: 659: 76.59		MO4L2_HUMAN (140-423): 2.06e-86: 266: 39.52
+	Hs
		1109736 HDAC1_HUMAN (3-443): 0: 637: 81.18		MO4L2_HUMAN (140-423): 2.06e-86: 266: 39.52
+	Sc
		739928 RPD3_YEAST (4-419): 0: 573: 59.81		EAF3_YEAST (17-419): 6.2e-88: 274: 24.89
+	Hs
		1195577 HDAC2_HUMAN (2-488): 0: 659: 76.59		ARI4B_HUMAN (12-257): 1.66e-44: 167: 14.29
+	Hs
		711784 HDAC2_HUMAN (2-488): 0: 659: 76.59		ARI4A_HUMAN (14-260): 4.4e-40: 155: 15.39
+	Hs
		1109782 HDAC1_HUMAN (3-443): 0: 637: 81.18		ARI4B_HUMAN (12-257): 1.66e-44: 167: 14.29
+	Hs
		711764 HDAC1_HUMAN (3-443): 0: 637: 81.18		ARI4A_HUMAN (14-260): 4.4e-40: 155: 15.39
+	Mm
		60132 HDAC4_MOUSE (5-405): 1.49e-134: 418: 23.83		ARI4B_MOUSE (12-267): 9.54e-46: 171: 16.22