HitPredict

Interactor 1: NDUA4 (O00483)
Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit)
Gene: NDUFA4

Interactor 2: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, proximity-dependent biotin identification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 1124
+	Hs
		137660 NDUA4_HUMAN (1-81): 4.79e-50: 153: 100.00		UFO_HUMAN (330-1106): 9.83e-161: 501: 23.47
+	Hs
		137706 NDUA4_HUMAN (1-81): 4.79e-50: 153: 100.00		TYRO3_HUMAN (351-1116): 3.22e-157: 492: 22.43
+	Hs
		137630 NDUA4_HUMAN (1-81): 4.79e-50: 153: 100.00		FGFR1_HUMAN (362-1124): 5.34e-157: 489: 23.52
+	Hs
		137652 NDUA4_HUMAN (1-81): 4.79e-50: 153: 100.00		FGFR4_HUMAN (338-1123): 8.91e-157: 488: 23.99
+	Hs
		137659 NDUA4_HUMAN (1-81): 4.79e-50: 153: 100.00		EPHA8_HUMAN (519-1110): 3.48e-151: 479: 21.58
+	Hs
		137623 NDUA4_HUMAN (1-81): 4.79e-50: 153: 100.00		ROS1_HUMAN (448-1123): 1.39e-128: 436: 24.41
+	Hs
		137709 NDUA4_HUMAN (1-81): 4.79e-50: 153: 100.00		MERTK_HUMAN (350-632): 2.97e-17: 89.7: 16.89