Interactor 1: HRS (Q960X8)
Hepatocyte growth factor-regulated tyrosine kinase substrate
Gene: HRS

Interactor 2: Q9XTL2 (Q9XTL2)
Jak pathway signal transduction adaptor molecule (LD02639p) (Signal transducing adaptor molecule) (Signal transducting adaptor protein)
Gene: Stam

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.852

The method score is based on:

Property Details
Experiments 14605208, 15710747, 38944040
Identification Methods two hybrid, two hybrid fragment pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE~VHS, VHS~VHS
Common GO terms GO:0016197 - endosomal transport
GO:0016322 - neuron remodeling
GO:0035091 - phosphatidylinositol binding
GO:0043130 - ubiquitin binding
GO:0051726 - regulation of cell cycle
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 760
Dm

1 689
+ Hs
+ Hs
+ Mm
+ Ce
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025