Protein: VPS27
Vacuolar protein sorting-associated protein 27 (Golgi retention defective protein 11)

Gene: VPS27
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: P40343

Gene Ontology (top 5):
GO:0005768 - endosome
GO:0005774 - vacuolar membrane
GO:0006623 - protein targeting to vacuole
GO:0006995 - cellular response to nitrogen starvation
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

803358

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

19

16

Small-scale

0.989

High

509585

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

10

20

Small-scale

0.875

High

677756

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

7

12

Small-scale

0.748

High

823088

VPS27
Vacuolar protein sorting-associated protein 27

1

17

Small-scale

0.710

High

645934

DBF2
Cell cycle protein kinase DBF2

2

5

Small-scale

0.550

High

823093

COPA
Coatomer subunit alpha

1

6

Small-scale

0.515

High

762829

TOR1
Serine/threonine-protein kinase TOR1

1

6

Small-scale

0.501

High

579503

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

707263

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

779951

DOA1
Protein DOA1

1

4

Small-scale

0.479

High

815018

SNF7
Vacuolar-sorting protein SNF7

1

5

High-throughput

0.479

High

815455

RSP5
E3 ubiquitin-protein ligase RSP5

1

19

High-throughput

0.479

High

823091

COPB2
Coatomer subunit beta'

1

6

Small-scale

0.479

High

823092

ENT3
Epsin-3

1

3

Small-scale

0.479

High

823095

VPS28
Vacuolar protein sorting-associated protein 28

1

4

Small-scale

0.479

High

823096

ENT5
Epsin-5

1

3

Small-scale

0.479

High

823097

SIZ1
E3 SUMO-protein ligase SIZ1

1

2

High-throughput

0.479

High

437928

KAPC
cAMP-dependent protein kinase type 3

1

2

High-throughput

0.457

High

574688

KSS1
Mitogen-activated protein kinase KSS1

1

3

High-throughput

0.457

High

642398

MCK1
Protein kinase MCK1

1

5

High-throughput

0.457

High

644790

CLH
Clathrin heavy chain

1

18

Small-scale

0.457

High

656792

KC12
Casein kinase I homolog 2

1

6

High-throughput

0.457

High

735508

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

2

High-throughput

0.457

High

758302

HSL1
Probable serine/threonine-protein kinase HSL1

1

3

High-throughput

0.457

High

801842

KSP1
Serine/threonine-protein kinase KSP1

1

4

High-throughput

0.457

High

823089

PRK1
Actin-regulating kinase PRK1

1

2

High-throughput

0.457

High

823094

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

11

High-throughput

0.457

High

823098

YP150
Putative serine/threonine-protein kinase YPL150W

1

2

High-throughput

0.457

High

823100

PKH2
Serine/threonine-protein kinase PKH2

1

7

Small-scale

0.457

High

823103

PRR2
Serine/threonine-protein kinase PRR2

1

6

High-throughput

0.457

High

365066

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.437

High

672673

BPH1
Beige protein homolog 1

1

4

High-throughput

0.437

High

823099

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.437

High

823102

RPN5
26S proteasome regulatory subunit RPN5

1

1

Small-scale

0.437

High

526845

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.407

High

741692

HSP7F
Heat shock protein homolog SSE1

1

18

High-throughput

0.407

High

804202

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.407

High

688799

RFA3
Replication factor A protein 3

1

0

High-throughput

0.249

Low

712796

CHS3
Chitin synthase 3

1

0

Small-scale

0.249

Low

740174

RPN2
26S proteasome regulatory subunit RPN2

1

0

Small-scale

0.249

Low

747697

ATO2
Ammonia transport outward protein 2

1

0

High-throughput

0.249

Low

823090

COPE
Coatomer subunit epsilon

1

0

Small-scale

0.249

Low

823101

LCB4
Sphingoid long chain base kinase 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025