Protein: HSE1
Class E vacuolar protein-sorting machinery protein HSE1

Gene: HSE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 67
UniProt ID: P38753

Gene Ontology (top 5):
GO:0005768 - endosome
GO:0005774 - vacuolar membrane
GO:0006623 - protein targeting to vacuole
GO:0009306 - protein secretion
GO:0010008 - endosome membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

803358

VPS27
Vacuolar protein sorting-associated protein 27

19

16

Small-scale

0.989

High

509534

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

5

20

Small-scale

0.811

High

803352

RSP5
E3 ubiquitin-protein ligase RSP5

2

20

Small-scale

0.807

High

779946

DOA1
Protein DOA1

4

3

Small-scale

0.707

High

744842

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

7

High-throughput

0.698

High

803349

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

16

High-throughput

0.698

High

677750

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

3

13

Small-scale

0.676

High

803359

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

3

13

Small-scale

0.629

High

803377

MYO5
Myosin-5

1

7

High-throughput

0.625

High

803354

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.584

High

803381

SKI7
Superkiller protein 7

2

3

High-throughput

0.577

High

803382

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

1

High-throughput

0.518

High

803365

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

High-throughput

0.518

High

803384

POC4
Proteasome chaperone 4

1

0

High-throughput

0.518

High

518012

SSBP1
Single-stranded nucleic acid-binding protein

1

7

High-throughput

0.494

High

577548

CYC8
General transcriptional corepressor CYC8

1

7

High-throughput

0.494

High

728704

ACBP
Acyl-CoA-binding protein

1

3

High-throughput

0.494

High

795635

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

10

High-throughput

0.494

High

797145

AIM3
Altered inheritance of mitochondria protein 3

1

12

High-throughput

0.494

High

803357

YTA12
Mitochondrial inner membrane m-AAA protease component YTA12

1

7

High-throughput

0.494

High

803360

NDC80
Kinetochore protein NDC80

1

20

High-throughput

0.494

High

803371

ACAC
Acetyl-CoA carboxylase

1

5

High-throughput

0.494

High

803373

BLH1
Cysteine proteinase 1, mitochondrial

1

1

High-throughput

0.494

High

803374

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

3

High-throughput

0.494

High

803375

MET31
Transcriptional regulator MET31

1

8

High-throughput

0.494

High

803376

HMO1
High mobility group protein 1

1

3

High-throughput

0.494

High

803385

HER1
HMG2-induced ER-remodeling protein 1

1

9

High-throughput

0.494

High

803387

LAS17
Proline-rich protein LAS17

1

18

High-throughput

0.494

High

803351

END3
Actin cytoskeleton-regulatory complex protein END3

1

17

High-throughput

0.481

High

803372

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

4

Small-scale

0.479

High

794840

CND2
Condensin complex subunit 2

1

1

High-throughput

0.470

High

803379

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.458

High

470130

SPS1
Sporulation-specific protein 1

1

15

High-throughput

0.457

High

803361

PRK1
Actin-regulating kinase PRK1

1

3

High-throughput

0.457

High

803362

AIM21
Altered inheritance of mitochondria protein 21

1

2

High-throughput

0.457

High

803370

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

3

High-throughput

0.439

High

523843

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.437

High

544757

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.437

High

707007

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

740909

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

9

High-throughput

0.437

High

795325

ATG8
Autophagy-related protein 8

1

6

High-throughput

0.437

High

803110

ECM29
Proteasome component ECM29

1

4

High-throughput

0.437

High

803355

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.407

High

803356

HUA1
Proline-rich protein HUA1

2

0

Small-scale

0.323

High

150093

YA11B
Truncated transposon Ty1-A Gag-Pol polyprotein

1

0

High-throughput

0.282

High

423587

ARGR2
Arginine metabolism regulation protein II

1

0

High-throughput

0.282

High

454441

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.282

High

673170

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.282

High

678271

ARE1
Sterol O-acyltransferase 1

1

0

High-throughput

0.282

High

763710

MTH1
Protein MTH1

1

0

High-throughput

0.282

High

798595

PAF1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.282

High

803350

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.282

High

803363

GLDS1
Protein GDS1

1

0

High-throughput

0.282

High

803369

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.282

High

803378

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.282

High

803380

BSP1
F-actin capping regulator BSP1

1

0

High-throughput

0.282

High

803353

YEC3
Uncharacterized protein YEL023C

1

0

High-throughput

0.269

Low

803366

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.261

Low

803367

YBP2
YAP1-binding protein 2

1

0

High-throughput

0.261

Low

60148

YM084
Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.251

Low

749667

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

796301

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

803364

SCD6
Protein SCD6

1

0

Small-scale

0.251

Low

803383

RUP1
UBA domain-containing protein RUP1

1

0

Small-scale

0.249

Low

803386

CSN10
COP9 signalosome complex subunit 10

1

0

Small-scale

0.249

Low

803368

YN82
Putative uncharacterized protein YNR005C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025