HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~PHD, Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 127 Hs			1 793
+	Hs
		1163159 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		UHRF1_HUMAN (1-793): 0: 890: 100.00
+	Hs
		754953 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		UHRF1_HUMAN (1-793): 0: 890: 100.00
+	Hs
		981035 H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04		UHRF1_HUMAN (1-793): 0: 890: 100.00
+	Mm
		533453 H2B1M_MOUSE (1-127): 1.38e-53: 166: 85.04		UHRF2_MOUSE (1-793): 0: 779: 54.50
+	Hs
		256932 H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25		CHD5_HUMAN (233-502): 2.38e-54: 206: 18.61
+	Hs
		980946 H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04		CHD5_HUMAN (233-502): 2.38e-54: 206: 18.61
+	Hs
		1088492 H2B1H_HUMAN (5-127): 5.54e-54: 166: 85.37		CHD3_HUMAN (101-502): 2.49e-51: 197: 13.90
+	Hs
		256848 H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25		CHD3_HUMAN (101-502): 2.49e-51: 197: 13.90
+	Hs
		754824 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		CHD3_HUMAN (101-502): 2.49e-51: 197: 13.90
+	Hs
		980730 H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04		CHD3_HUMAN (101-502): 2.49e-51: 197: 13.90
+	Hs
		1132729 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CHD4_HUMAN (233-502): 1.61e-48: 188: 15.00
+	Hs
		1132877 H2B1H_HUMAN (5-127): 5.54e-54: 166: 85.37		CHD4_HUMAN (233-502): 1.61e-48: 188: 15.00
+	Hs
		256858 H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25		CHD4_HUMAN (233-502): 1.61e-48: 188: 15.00
+	Hs
		754848 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		CHD4_HUMAN (233-502): 1.61e-48: 188: 15.00
+	Hs
		980773 H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04		CHD4_HUMAN (233-502): 1.61e-48: 188: 15.00
+	Hs
		981167 H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04		BAZ2A_HUMAN (138-417): 2.78e-39: 159: 17.87
+	Hs
		1163264 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		KDM5B_HUMAN (227-383): 2.49e-32: 137: 20.35
+	Hs
		302542 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		RNF8_HUMAN (578-785): 2.86e-32: 133: 17.23
+	Hs
		302399 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		RNF8_HUMAN (578-785): 2.86e-32: 133: 17.23
+	Hs
		161419 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		KMT2D_HUMAN (313-363): 2.88e-11: 69.9: 48.08